Purpose Tumor associated macrophages (TAMs) are considered with the capacity to have
both negative and positive effects on tumor growth. The prognostic value of TAM for survival …

Quercetin, a widely distributed bioflavonoid, inhibits the growth of tumor cells. The present
study was designed to investigate the possible involvement of apoptosis and heat shock …

The breaking of immune tolerance against autologous angiogenic endothelial cells should
be a useful approach for cancer therapy. Here we show that immunotherapy of tumors using …

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
continually poses serious threats to global public health. The main protease (M pro …

With the improvement of gene vectors, the rise of chimeric antigen receptor T cell immunotherapy
and breakthroughs in the genome editing technology, gene therapy had once again …

tRNA-derived small RNA (tsRNA) is a novel regulatory small non-coding RNA and participates
in diverse physiological and pathological processes. However, the presence of tsRNAs in …

CRISPR/Cas9 genome editing platforms are widely applied as powerful tools in basic research
and potential therapeutics for genome regulation. The appropriate alternative of delivery …

Emerging SARS-CoV-2 variants continue to cause waves of new infections globally.
Developing effective antivirals against SARS-CoV-2 and its variants is an urgent task. The main …

Purpose: Quercetin is a potent chemotherapeutic drug. Clinical trials exploring different
schedules of administration of quercetin have been hampered by its extreme water insolubility. …

The chemokine receptor CXCR2 and its ligands are implicated in the progression of tumours
and various inflammatory diseases. Activation of the CXCLs/CXCR2 axis activates multiple …