Voltage-gated K + channels comprise the largest and most diverse class of ion channels.
These channels establish the resting membrane potential and modulate the frequency and …

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) is part of a complex
signaling system that affects a variety of important cell functions. PTEN blocks the action of …

Isocyanate chemicals, including toluene diisocyanate (TDI), are currently the most common
causes of occupational asthma. Although considerable controversy remains regarding its …

Lysophosphatidic acid (LPA) is elevated in ascites of ovarian cancer patients and stimulates
growth and other activities of ovarian cancer cells in vitro. Tissue hypoxia is a critical factor …

The purpose of this study was to examine the direct effects of propofol on ischemia-reperfusion
injury using an isolated Langendorff rat heart preparation. Hearts were perfused with …

The RNA world hypothesis presumes that RNA will be competent for varied essential cellular
functions. One such indispensable cell function is regulation of membrane permeability. …

Atrial natriuretic peptide (ANP) is a cardiac peptide, the transcription of which is up-regulated
in the ischaemic ventricle. However, the molecular mechanism of ANP induction is unclear. …

Junctin is a 26‐kDa integral membrane protein, colocalized with the ryanodine receptor (RyR)
and calsequestrin at the junctional sarcoplasmic reticulum (SR) membrane in cardiac and …

The human Kv1.5 potassium channel forms the I Kur current in atrial myocytes and is functionally
altered by coexpression with Kvβ subunits. To explore the role of protein kinase A (PKA…

This study shows whether increased intracellular cAMP level by cilostazol is directly coupled
to its maxi-K channel activation in human endothelial cells. Cilostazol (1 μM) increased the …