Neuroprotective effect of green tea extract in experimental ischemia-reperfusion brain injury

…, SR Ryu, HJ Kim, JK Lee, SH Lee, DB Kim, YP Yun… - Brain research …, 2000 - Elsevier
Eicosanoids accumulation and formation of oxygen free radicals have been implicated in
the pathogenesis of ischemia/reperfusion brain injury. In the present study, we examined …

The isolation and antioxidative effects of vitexin fromAcer palmatum

…, JH Kim, GS Sim, DH Lee, KE Lee, YP Yun… - Archives of pharmacal …, 2005 - Springer
Free radicals and reactive oxygen species (ROS) caused by UV exposure or other environmental
factors are critical players in cellular damage and aging. In order to develop a new …

[HTML][HTML] Green tea (-)-epigallocatechin-3-gallate inhibits β-amyloid-induced cognitive dysfunction through modification of secretase activity via inhibition of ERK and …

JW Lee, YK Lee, JO Ban, TY Ha, YP Yun, SB Han… - The Journal of …, 2009 - Elsevier
Alzheimer’s disease (AD) is characterized by the extracellular deposition of β-amyloid peptide
(Aβ) in cerebral plaques. Aβ is derived from the β-amyloid precursor protein (APP) by the …

Acemannan purified from Aloe vera induces phenotypic and functional maturation of immature dendritic cells

JK Lee, MK Lee, YP Yun, Y Kim, JS Kim, YS Kim… - International …, 2001 - Elsevier
Acemannan, a major carbohydrate fraction of Aloe vera gel, has been known to have antiviral
and antitumoral activities in vivo through activation of immune responses. The present …

Structure activity relationship of antioxidative property of flavonoids and inhibitory effect on matrix metalloproteinase activity in UVA-irradiated human dermal fibroblast

…, JH Kim, HB Pyo, DC Moon, KW Oh, YP Yun… - Archives of pharmacal …, 2007 - Springer
Collagenase, a matrix metalloproteinases (MMPs), is a key regulator in the photoaging
process of skin due to the reactive oxygen species generated after exposure to ultraviolet A (UVA)…

(−)-Epigallocatechin-3-gallate prevents lipopolysaccharide-induced elevation of beta-amyloid generation and memory deficiency

…, DY Yuk, JW Lee, SY Lee, TY Ha, KW Oh, YP Yun… - Brain research, 2009 - Elsevier
Neuroinflammation has been known to play a role in the pathogenesis of AD. Our previous
study showed that lipopolysaccharide (LPS) induced memory impairment through the …

Antithrombotic activities of green tea catechins and (−)-epigallocatechin gallate

…, DY Yuk, KH Chung, JB Park, HS Yoo, YP Yun - Thrombosis research, 1999 - Elsevier
The antithrombotic activities and mode of action of green tea catechins (GTC) and (−)-epigallocatechin
gallate (EGCG), a major compound of GTC, were investigated. Effects of GTC and …

Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties

YJ Lee, DY Choi, YP Yun, SB Han, KW Oh… - The Journal of nutritional …, 2013 - Elsevier
Neuroinflammation has been known to play a critical role in the pathogenesis of Alzheimer's
disease (AD) through amyloidogenesis. In a previous study, we found that systemic …

Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice

…, JY Yu, MK Lee, YM Lee, JT Hong, YP Yun… - The Journal of nutritional …, 2014 - Elsevier
Obesity is associated with metabolic disorders. Sulforaphane, an isothiocyanate, inhibits
adipogenesis and the occurrence of cardiovascular disease. In this study, we investigated …

Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-κB

…, SY Lee, JS Cho, SM Son, SS Choi, YP Yun… - European journal of …, 2010 - Elsevier
Ginsenoside Rg3 has been a subject of interest for use as a cancer preventive or therapeutic
agent. Nuclear factor-kappa (NF-κB) is constitutively activated in prostate cancer, and gives …