Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by interstitial remodelling,
leading to compromised lung function. Cellular senescence markers are detectable within …

It is now established that airway smooth muscle (ASM) has roles in determining airway structure
and function, well beyond that as the major contractile element. Indeed, changes in ASM …

Sex differences in the biology of different organ systems and the influence of sex hormones
in modulating health and disease are increasingly relevant in clinical and research areas. …

There is increasing appreciation that mitochondria serve cellular functions beyond oxygen
sensing and energy production. Accordingly, it has become important to explore …

Herein, we demonstrate that the surface charge of gold nanoparticles (AuNPs) plays a critical
role in modulating membrane potential of different malignant and nonmalignant cell types …

INTRODUCTION The COVID-19 pandemic revealed enhanced vulnerability of the elderly and
chronically ill to adverse outcomes upon severe acute respiratory syndrome coronavirus 2 …

There is marked sexual dimorphism in the current coronavirus disease 2019 (COVID-19)
pandemic. Here we report that estrogen can regulate the expression of angiotensin-converting …

The balance between mitochondrial fission and fusion is crucial for mitochondria to perform
its normal cellular functions. We hypothesized that cigarette smoke (CS) disrupts this …

Fredberg, JJ, KA Jones, M. Nathan, S. Raboudi, YS Prakash, SA Shore, JP Butler, and GC
Sieck. Friction in airway smooth muscle: mechanism, latch, and implications in asthma. J. Appl…

Tissue-resident memory CD8 + T (Trm) cells share core residency gene programs with
tumor-infiltrating lymphocytes (TILs). However, the transcriptional, metabolic, and epigenetic …