Mitochondrial diseases

…, PF Chinnery, S DiMauro, M Hirano, Y Koga… - Nature reviews Disease …, 2016 - nature.com
Mitochondrial diseases are a group of genetic disorders that are characterized by defects in
oxidative phosphorylation and caused by mutations in genes in the nuclear DNA (nDNA) …

Biosynthesis of ether-type polar lipids in archaea and evolutionary considerations

Y Koga, H Morii - Microbiology and Molecular Biology Reviews, 2007 - Am Soc Microbiol
… A first search for CDP-diacylglycerol synthase homologs in archaea did not yield significant
hits (Y. Koga, unpublished results). From a database search of 22 archaeal species whose …

Ether polar lipids of methanogenic bacteria: structures, comparative aspects, and biosyntheses

Y Koga, M Nishihara, H Morii… - Microbiological …, 1993 - Am Soc Microbiol
… have been identified by Nishihara and Koga (85). The hydroxyarchaeol-containing
phospholipids hydroxyarchaetidylserine and hydroxyarchaetidylinositol (Fig. 10) were identified, as …

Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice

…, N Oyama, XN Yu, C Kubo, Y Koga - The Journal of …, 2004 - Wiley Online Library
Indigenous microbiota have several beneficial effects on host physiological functions;
however, little is known about whether or not postnatal microbial colonization can affect the …

The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction.

…, K Tanaka, Y Aiba, C Kubo, Y Koga - … (Baltimore, Md.: 1950 …, 1997 - journals.aai.org
… On the other hand, the level of IFN-y, a cytokine preferentially synthesized by Thl cells, … after
72 h for measurements of IL-2 and IFN-y, and after 96 h for measurements of IL-4 and TGF-/3…

Fgf10 is essential for limb and lung formation

…, T Yoshizawa, T Sato, N Yagishita, D Matsui, Y Koga… - Nature …, 1999 - nature.com
The interactions between fibroblast growth factors (FGF) and their receptors have important
roles in mediating mesenchymal-epithelial cell interactions during embryogenesis 1, 2. In …

Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre syndrome

…, S Servidei, I Nonaka, Y Koga… - … England Journal of …, 1989 - Mass Medical Soc
We investigated the correlations of deletions of mitochondrial DNA in skeletal muscle with
clinical manifestations of mitochondrial myopathies, a group of disorders defined either by …

Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)

…, S Shimojo, T Koori, M Mora, JE Riggs, SJ Oh, Y Koga… - Nature, 2000 - nature.com
… Black boxes represent the loops created between two cysteine residues flanking each of
the four loop regions; Y depicts a glycosylation site; hatched boxes show altered amino acids …

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

…, T Kimura, K Yoshihara, Y Koga… - American Journal …, 2012 - journals.physiology.org
… Author contributions: Y. Asano and NS conception and design of research; Y. Asano, TH,
RN, … Asano prepared figures; Y. Asano and NS drafted manuscript; …

Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy

…, M Matsuzaki, T Sakamoto, H Toshima, Y Koga… - Nature …, 1997 - nature.com
Hypertrophic cardiomyopathy (HCM), the most common cause of sudden death in the young,
is an autosomal dominant disease characterized by ventricular hypertrophy accompanied …