Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma

YX Zhu, KM Kortuem, AK Stewart - Leukemia & lymphoma, 2013 - Taylor & Francis
Although several mechanisms have been proposed to explain the activity of thalidomide,
lenalidomide and pomalidomide in multiple myeloma (MM), including demonstrable anti-…

How cotton fibers elongate: a tale of linear cell-growth mode

YM Qin, YX Zhu - Current opinion in plant biology, 2011 - Elsevier
Cotton fibers (cotton lint) are single-celled trichomes that differentiate from the ovule epidermis.
Unidirectional and fast-growing cells generally expand at the dome-shaped apical zone (…

Recent advances and future perspectives in cotton research

…, JQ Huang, XY Chen, YX Zhu - Annual review of plant …, 2021 - annualreviews.org
Cotton is not only the world's most important natural fiber crop, but it is also an ideal system
in which to study genome evolution, polyploidization, and cell elongation. With the assembly …

[HTML][HTML] The draft genome of a diploid cotton Gossypium raimondii

…, C Song, N Shi, RJ Kohel, RG Percy, JZ Yu, YX Zhu… - Nature …, 2012 - nature.com
We have sequenced and assembled a draft genome of G. raimondii, whose progenitor is
the putative contributor of the D subgenome to the economically important fiber-producing …

[PDF][PDF] Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma

…, CX Shi, M Sebag, E Braggio, T Henry, YX Zhu… - Cancer cell, 2007 - cell.com
Activation of NF-κB has been noted in many tumor types, however only rarely has this been
linked to an underlying genetic mutation. An integrated analysis of high-density …

[HTML][HTML] Genome sequence of the cultivated cotton Gossypium arboreum

…, J Wang, K Liu, RJ Kohel, RG Percy, JZ Yu, YX Zhu… - Nature …, 2014 - nature.com
The complex allotetraploid nature of the cotton genome (AADD; 2n = 52) makes genetic,
genomic and functional analyses extremely challenging. Here we sequenced and assembled …

Transcriptome profiling, molecular biological, and physiological studies reveal a major role for ethylene in cotton fiber cell elongation

…, L Zhang, J Cheng, LP Wei, ZY Wang, YX Zhu - The plant …, 2006 - academic.oup.com
Upland cotton (Gossypium hirsutum) produces the most widely used natural fibers, yet the
regulatory mechanisms governing fiber cell elongation are not well understood. Through …

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

YX Zhu, E Braggio, CX Shi, LA Bruins… - Blood, The Journal …, 2011 - ashpublications.org
The precise molecular mechanism of action and targets through which thalidomide and
related immunomodulatory drugs (IMiDs) exert their antitumor effects remains unclear. We …

Correlation between Indian Ocean summer monsoon and North Atlantic climate during the Holocene

YT Hong, B Hong, QH Lin, YX Zhu, Y Shibata… - Earth and Planetary …, 2003 - Elsevier
There has been a number of investigations for the correlation between the Asia monsoon and
the North Atlantic climate for the last glacial; however, little research has been done for the …

HXMT identification of a non-thermal X-ray burst from SGR J1935+ 2154 and with FRB 200428

…, ZL Zhang, DK Zhou, JF Zhou, Y Zhu, YX Zhu… - Nature …, 2021 - nature.com
Fast radio bursts (FRBs) are short pulses observed in the radio band from cosmological
distances 1 . One class of models invokes soft gamma-ray repeaters (SGRs), or magnetars, as …