Neurobiology of cocaine abuse

WL Woolverton, KM Johnson - Trends in pharmacological sciences, 1992 - cell.com
The recent escalation of cocaine abuse has increased awareness of the need to understand
the behavioral effects of cocaine and the determinants of those effects. Cocaine alters both …

Effects of increasing the magnitude of an alternative reinforcer on drug choice in a discrete-trials choice procedure

MA Nader, WL Woolverton - Psychopharmacology, 1991 - Springer
Rhesus monkeys were trained in a discretetrials choice procedure and allowed to choose
between food delivery (1–16 pellets; 1 g/pellet) and intravenous injections of cocaine (0.03–…

Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs

…, RB Rothman, BE Blough, WL Woolverton - … of Pharmacology and …, 2005 - ASPET
It has been reported that among drugs with mixed actions on central nervous system
monoamine systems, increased serotonergic activity is associated with decreased potency as a …

Long-term effects of chronic methamphetamine administration in rhesus monkeys

WL Woolverton, GA Ricaurte, LS Forno, LS Seiden - Brain research, 1989 - Elsevier
Biochemical and neuropathological effects of exposure to a high dose regimen of
methamphetamine were evaluated in rhesus monkeys approximately 4 years after the last drug …

Elevated level of metabotropic glutamate receptor 2/3 in the prefrontal cortex in major depression

AM Feyissa, WL Woolverton, JJ Miguel-Hidalgo… - Progress in Neuro …, 2010 - Elsevier
Clinical, postmortem and preclinical research strongly implicates dysregulation of
glutamatergic neurotransmission in major depressive disorder (MDD). Recently, metabotropic …

Intravenous self-administration of dopamine receptor agonists by rhesus monkeys.

WL Woolverton, LI Goldberg, JZ Ginos - Journal of Pharmacology and …, 1984 - ASPET
Pharmacological studies have provided important information relevant to the behavioral
role of central nervous system (CNS) dopamine (DA) as well as the existence of multiple DA …

Effects of clomipramine on self-control choice in Lewis and Fischer 344 rats

KG Anderson, WL Woolverton - Pharmacology Biochemistry and Behavior, 2005 - Elsevier
Rates of delay discounting (impulsive choice) have been shown to vary among individuals,
particularly people who abuse drugs relative to those who do not, but factors that may …

[HTML][HTML] Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression

…, MC Austin, J Wang, IA Paul, WL Woolverton… - Journal of Biological …, 2012 - ASBMB
Chronic stress is a risk factor for psychiatric illnesses, including depressive disorders, and is
characterized by increased blood glucocorticoids and brain monoamine oxidase A (MAO A, …

Effects of increasing response requirement on choice between cocaine and food in rhesus monkeys

MA Nader, WL Woolverton - Psychopharmacology, 1992 - Springer
Rhesus monkeys were trained in a discretetrials choice procedure and allowed to choose
between intravenous injections of cocaine (0.01–1.0 mg/kg/injection) and food presentation (1 …

Oligodendrocyte morphometry and expression of myelin–Related mRNA in ventral prefrontal white matter in major depressive disorder

…, AH Iyo, M Moulana, PB Kyle, WL Woolverton… - Journal of psychiatric …, 2015 - Elsevier
White matter disturbance in the ventral prefrontal cortex (vPFC) in major depressive disorder
(MDD) has been noted with diffusion tensor imaging (DTI). However, the cellular and …