The Chemistry of Neutron Capture Therapy. (Chem. Rev. 1998, 98, 1515. Published on the Web May 20, 1998)
AH Soloway, W Tjarks, BA Barnum, FG Rong… - Chemical …, 1998 - ACS Publications
… Soloway,* Werner Tjarks, Beverly A. Barnum, Feng-Guang Rong, Rolf F. Barth, Iwona M. …
Site-specific conjugation of boron-containing dendrimers to anti-EGF receptor monoclonal antibody cetuximab (IMC-C225) and its evaluation as a potential delivery …
…, RF Barth, W Yang, M Chatterjee, W Tjarks… - Bioconjugate …, 2004 - ACS Publications
The gene encoding EGFR often is amplified in human gliomas, and the receptor itself has
been considered as a potential target for the specific delivery of therapeutic agents to brain …
been considered as a potential target for the specific delivery of therapeutic agents to brain …
Synthesis and biological evaluation of folate receptor-targeted boronated PAMAM dendrimers as potential agents for neutron capture therapy
Successful treatment of cancer by boron neutron capture therapy (BNCT) requires the selective
delivery of 10 B to constituent cells within a tumor. The expression of the folate receptor …
delivery of 10 B to constituent cells within a tumor. The expression of the folate receptor …
Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature
…, BTS Thirumamagal, W Tjarks… - Molecular cancer …, 2005 - AACR
Tumor neovasculature is a potential but, until very recently, unexplored target for boron neutron
capture therapy (BNCT) of cancer. In the present report, we describe the construction of …
capture therapy (BNCT) of cancer. In the present report, we describe the construction of …
[HTML][HTML] A novel pH-sensitive liposome formulation containing oleyl alcohol
JJ Sudimack, W Guo, W Tjarks, RJ Lee - Biochimica et Biophysica Acta …, 2002 - Elsevier
… Author links open overlay panel Jennifer J Sudimack a , Wenjin Guo a , Werner Tjarks b ,
Robert J Lee a …
Robert J Lee a …
Boron neutron capture therapy of brain tumors: an emerging therapeutic modality
…, N Gupta, TE Blue, W Yang, W Tjarks - …, 1999 - journals.lww.com
BORON NEUTRON CAPTURE therapy (BNCT) is based on the nuclear reaction that occurs
when boron-10, a stable isotope, is irradiated with low-energy thermal neutrons to yield α …
when boron-10, a stable isotope, is irradiated with low-energy thermal neutrons to yield α …
Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR
X Pan, G Wu, W Yang, RF Barth, W Tjarks… - Bioconjugate …, 2007 - ACS Publications
The objective of the present study was to construct epidermal growth factor receptor (EGFR)
targeting cetuximab-immunoliposomes (ILs) for targeted delivery of boron compounds to …
targeting cetuximab-immunoliposomes (ILs) for targeted delivery of boron compounds to …
Molecular targeting and treatment of an epidermal growth factor receptor–positive glioma using boronated cetuximab
…, M Swindall, AK Bandyopadhyaya, W Tjarks… - Clinical cancer …, 2007 - AACR
Purpose: The purpose of the present study was to evaluate the anti–epidermal growth factor
monoclonal antibody (mAb) cetuximab (IMC-C225) as a delivery agent for boron neutron …
monoclonal antibody (mAb) cetuximab (IMC-C225) as a delivery agent for boron neutron …
Molecular targeting and treatment of composite EGFR and EGFRvIII-positive gliomas using boronated monoclonal antibodies
…, MR Swindall, AK Bandyopadhyaya, W Tjarks… - Clinical Cancer …, 2008 - AACR
Purpose: The purpose of the present study was to evaluate the anti–epidermal growth factor
receptor (EGFR) monoclonal antibody (mAb), cetuximab, (IMC-C225) and the anti-EGFRvIII …
receptor (EGFR) monoclonal antibody (mAb), cetuximab, (IMC-C225) and the anti-EGFRvIII …
Carborane clusters in computational drug design: a comparative docking evaluation using AutoDock, FlexX, Glide, and Surflex
…, R Pavlovicz, C Li, W Tjarks - Journal of chemical …, 2009 - ACS Publications
Compounds containing boron atoms play increasingly important roles in the therapy and
diagnosis of various diseases, particularly cancer. However, computational drug design of …
diagnosis of various diseases, particularly cancer. However, computational drug design of …