Origin of the Difference in Order−Disorder Transition Temperature between Polystyrene-block-poly(2-vinylpyridine) and Polystyrene-block-poly(4-vinylpyridine) …

W Zha, CD Han, DH Lee, SH Han, JK Kim… - …, 2007 - ACS Publications
Three polystyrene-block-poly(2-vinylpyridine) (S2VP diblock) and three polystyrene-block-poly(4-vinylpyridine)
(S4VP diblock) copolymers with varying molecular weights and block …

Metabolomic investigation into variation of endogenous metabolites in professional athletes subject to strength-endurance training

…, H Lu, X Huang, Y Liu, W Zha… - Journal of Applied …, 2009 - journals.physiology.org
Strength-endurance type of sport can lead to modification of human beings' physiological
status. The present study aimed to investigate the alteration of metabolic phenotype or …

[HTML][HTML] The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease

RN Schuck, W Zha, ML Edin, A Gruzdev, KC Vendrov… - PloS one, 2014 - journals.plos.org
Fatty liver disease is an emerging public health problem without effective therapies, and
chronic hepatic inflammation is a key pathologic mediator in its progression. Cytochrome P450 (…

GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy

M Li, X Wang, J Aa, W Qin, W Zha… - American Journal …, 2013 - journals.physiology.org
Early diagnosis of diabetic nephropathy (DN) is difficult although it is of crucial importance
to prevent its development. To probe potential markers and the underlying mechanism of DN, …

Serum metabolomic profiling in patients with systemic lupus erythematosus by GC/MS

…, C Zhang, X Hu, M Gao, A Shi, W Zha… - Modern …, 2016 - academic.oup.com
Objectives: The aim of this study is to characterize the serum metabolic profiles of patients
with systemic lupus erythematosus (SLE) using metabolomics. Methods: Serum samples were …

[HTML][HTML] Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages

W Zha, G Liang, J Xiao, EJ Studer, PB Hylemon… - PLoS …, 2010 - journals.plos.org
Background HIV protease inhibitor (PI)-induced inflammatory response plays an important
role in HIV PI-associated dyslipidemia and cardiovascular complications. This study …

[HTML][HTML] Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity

W Zha, ML Edin, KC Vendrov, RN Schuck, FB Lih… - Journal of lipid …, 2014 - ASBMB
Adipogenesis plays a critical role in the initiation and progression of obesity. Although
cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) have emerged as a potential …

HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells

X Wu, L Sun, W Zha, E Studer, E Gurley, L Chen… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Human immunodeficiency virus (HIV) protease inhibitor (PI)-induced
adverse effects have become a serious clinical problem. In addition to their metabolic and …

A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine

…, R Sun, Y Tang, JL Paletta, XL Wu, L Liu, W Zha… - Molecular …, 2015 - pubs.rsc.org
Clinical and animal studies demonstrated that orally administered berberine had a distinct
lipid-lowering effect. However, pharmacokinetic studies showed that berberine was poorly …

[HTML][HTML] Metabolomic approach to evaluating adriamycin pharmacodynamics and resistance in breast cancer cells

B Cao, M Li, W Zha, Q Zhao, R Gu, L Liu, J Shi, J Zhou… - Metabolomics, 2013 - Springer
Continuous exposure of breast cancer cells to adriamycin induces high expression of P-gp
and multiple drug resistance. However, the biochemical process and the underlying …