(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3, 3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R, 3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl) …

W Wannamaker, R Davies, M Namchuk, J Pollard… - … of Pharmacology and …, 2007 - ASPET
… In this report, we characterized another approach to suppress excessive inflammation in
diseases by inhibiting the ICE/caspase-1 subfamily of caspases essential for generation of …

Bacteriocins of gram-positive bacteria

JR Tagg, AS Dajani, LW Wannamaker - Bacteriological reviews, 1976 - Am Soc Microbiol
INTRODUCTION nants. Although earlier reviewers have kept Until recent years most definitive
investiga-pace with developments in the investigations of tions in the field of bacteriocins …

Differences between streptococcal infections of the throat and of the skin

LW Wannamaker - New England Journal of Medicine, 1970 - Mass Medical Soc
Antibody Response Variation in the streptococcal immune response related to the site of
infection (Tables 1 and 4 ) is supported by a growing body of information with pervasive …

Prevention of rheumatic fever: treatment of the preceding streptococcic infection

FW Denny, LW Wannamaker, WR Brink… - Journal of the …, 1950 - jamanetwork.com
The prevention of acute rheumatic fever by the prompt treatment of streptococcic infections
with penicillin has been attempted in this study. The results obtained show that this attempt …

Prophylaxis of acute rheumatic fever: by treatment of the preceding streptococcal infection with various amounts of depot penicillin

LW Wannamaker, CH Rammelkamp Jr… - The American journal of …, 1951 - Elsevier
The prevention of acute rheumatic fever by penicillin therapy of acute streptococcal respiratory
infections was attempted in this study. Procaine penicillin G in oil containing 2 per cent …

Diagnosis of streptococcal pharyngitis: differentiation of active infection from the carrier state in the symptomatic child

…, FH Top, BA Dudding, LW Wannamaker - The Journal of infectious …, 1971 - JSTOR
The finding of group A streptococci in patients with nasopharyngitis may be misleading as to
the nature of the current illness. This is especially true in children, in whom carrier rates for …

The chain that links the heart to the throat

LW WANNAMAKER - Circulation, 1973 - Am Heart Assoc
we must be guarded in our optimism that this trend will continue forever downward. Above
all, we … answer to the rheumatic fever problem, thatall we have to do is improve our delivery of …

Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2

…, M Murcko, T Wang, MW Wannamaker… - Journal of medicinal …, 2014 - ACS Publications
In our effort to develop agents for the treatment of influenza, a phenotypic screening approach
utilizing a cell protection assay identified a series of azaindole based inhibitors of the cap-…

Zirconocene complexes of imines. General synthesis, structure, reactivity, and in situ generation to prepare geometrically pure allylic amines

…, BT Watson, MW Wannamaker… - Journal of the …, 1989 - ACS Publications
We have recently reported several examples of such a synthetic tack.5 Due to the … complexes
of imines we endeavored to devise a general route to such complexes. We felt that the use …

The influence of the site of infection on the immune response to group A streptococci

…, EM Ayoub, LW Wannamaker - The Journal of …, 1970 - Am Soc Clin Investig
The immune response after streptococcal infection of the skin and of the upper respiratory
tract (URT) was studied prospectively in a group of normal children, ages 3-6 yr. The children …