Haplotyping germline and cancer genomes with high-throughput linked-read sequencing

…, JY Lee, K Belhocine, KM Giorda, WH Heaton… - Nature …, 2016 - nature.com
Haplotyping of human chromosomes is a prerequisite for cataloguing the full repertoire of
genetic variation. We present a microfluidics-based, linked-read sequencing technology that …

[HTML][HTML] Multi-platform discovery of haplotype-resolved structural variation in human genomes

…, DU Gorkin, M Gujral, V Guryev, WH Heaton… - Nature …, 2019 - nature.com
The incomplete identification of structural variants (SVs) from whole-genome sequencing
data limits studies of human genetic diversity and disease association. Here, we apply a suite …

Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl

EF Nemeth, WH Heaton, M Miller, J Fox… - … of Pharmacology and …, 2004 - ASPET
Calcimimetic compounds, which activate the parathyroid cell Ca 2+ receptor (CaR) and
inhibit parathyroid hormone (PTH) secretion, are under experimental study as a treatment for …

Plasma apolipoprotein A-1 absence associated with a marked reduction of high density lipoproteins and premature coronary artery disease.

EJ Schaefer, WH Heaton, MG Wetzel… - … : An Official Journal of …, 1982 - Am Heart Assoc
A 45-year-old woman with corneal opacification and severe coronary artery disease was
noted to have the following plasma lipid levels (mg/dl, +/- SD): total cholesterol 111 +/- 13, …

Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway

…, J Hu, J Yan, JM Walthall, A Mukherjee, WH Heaton… - Stem Cells, 2014 - academic.oup.com
The bone morphogenetic protein antagonist Gremlin 2 (Grem2) is required for atrial differentiation
and establishment of cardiac rhythm during embryonic development. A human Grem2 …

[HTML][HTML] Familial apolipoprotein AI and C-III deficiency, variant II.

…, ML Kashyap, LS Srivastava, WH Heaton… - Journal of Lipid …, 1985 - Elsevier
The biochemical, clinical, and genetic features were examined in the proband (homozygote)
and heterozygotes (n = 17) affected with familial apolipoprotein AI and C-III deficiency, …

Beneficial effect of physical training on blood flow to myocardium perfused by chronic collaterals in the exercising dog.

WH Heaton, KC Marr, NL Capurro, RE Goldstein… - Circulation, 1978 - Am Heart Assoc
To determine the effect of physical training on collateral blood flow, we measured regional
myocardial blood flow (MBF) by injecting 15 mu radioactive microspheres at rest and during …

Evidence for and implications of self-healing pulses of slip in earthquake rupture

TH Heaton - Physics of the Earth and Planetary Interiors, 1990 - Elsevier
Dislocation time histories of models derived from waveforms of seven earthquakes are
discussed. In each model, dislocation rise times (the duration of slip for a given point on the fault) …

An overview of OSHA regulations.

WH Heaton - Medical Group Management Journal, 1993 - europepmc.org
While it is true that chances of an OSHA survey are low, OSHA representatives are placing
top priority on employee complaints by investigating every one they receive. Author WH

Prof. WH Heaton

HTH Piaggio - Nature, 1941 - nature.com
WH Heaton | Nature … WH HeatonWH Heaton at the age of eighty–five brought to an
end a personal association with University College, Nottingham, almost from its beginning. …