Haplotyping germline and cancer genomes with high-throughput linked-read sequencing
…, JY Lee, K Belhocine, KM Giorda, WH Heaton… - Nature …, 2016 - nature.com
Haplotyping of human chromosomes is a prerequisite for cataloguing the full repertoire of
genetic variation. We present a microfluidics-based, linked-read sequencing technology that …
genetic variation. We present a microfluidics-based, linked-read sequencing technology that …
[HTML][HTML] Multi-platform discovery of haplotype-resolved structural variation in human genomes
The incomplete identification of structural variants (SVs) from whole-genome sequencing
data limits studies of human genetic diversity and disease association. Here, we apply a suite …
data limits studies of human genetic diversity and disease association. Here, we apply a suite …
Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl
EF Nemeth, WH Heaton, M Miller, J Fox… - … of Pharmacology and …, 2004 - ASPET
Calcimimetic compounds, which activate the parathyroid cell Ca 2+ receptor (CaR) and
inhibit parathyroid hormone (PTH) secretion, are under experimental study as a treatment for …
inhibit parathyroid hormone (PTH) secretion, are under experimental study as a treatment for …
Plasma apolipoprotein A-1 absence associated with a marked reduction of high density lipoproteins and premature coronary artery disease.
EJ Schaefer, WH Heaton, MG Wetzel… - … : An Official Journal of …, 1982 - Am Heart Assoc
A 45-year-old woman with corneal opacification and severe coronary artery disease was
noted to have the following plasma lipid levels (mg/dl, +/- SD): total cholesterol 111 +/- 13, …
noted to have the following plasma lipid levels (mg/dl, +/- SD): total cholesterol 111 +/- 13, …
Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway
…, J Hu, J Yan, JM Walthall, A Mukherjee, WH Heaton… - Stem Cells, 2014 - academic.oup.com
The bone morphogenetic protein antagonist Gremlin 2 (Grem2) is required for atrial differentiation
and establishment of cardiac rhythm during embryonic development. A human Grem2 …
and establishment of cardiac rhythm during embryonic development. A human Grem2 …
[HTML][HTML] Familial apolipoprotein AI and C-III deficiency, variant II.
…, ML Kashyap, LS Srivastava, WH Heaton… - Journal of Lipid …, 1985 - Elsevier
The biochemical, clinical, and genetic features were examined in the proband (homozygote)
and heterozygotes (n = 17) affected with familial apolipoprotein AI and C-III deficiency, …
and heterozygotes (n = 17) affected with familial apolipoprotein AI and C-III deficiency, …
Beneficial effect of physical training on blood flow to myocardium perfused by chronic collaterals in the exercising dog.
WH Heaton, KC Marr, NL Capurro, RE Goldstein… - Circulation, 1978 - Am Heart Assoc
To determine the effect of physical training on collateral blood flow, we measured regional
myocardial blood flow (MBF) by injecting 15 mu radioactive microspheres at rest and during …
myocardial blood flow (MBF) by injecting 15 mu radioactive microspheres at rest and during …
Evidence for and implications of self-healing pulses of slip in earthquake rupture
TH Heaton - Physics of the Earth and Planetary Interiors, 1990 - Elsevier
Dislocation time histories of models derived from waveforms of seven earthquakes are
discussed. In each model, dislocation rise times (the duration of slip for a given point on the fault) …
discussed. In each model, dislocation rise times (the duration of slip for a given point on the fault) …
An overview of OSHA regulations.
WH Heaton - Medical Group Management Journal, 1993 - europepmc.org
While it is true that chances of an OSHA survey are low, OSHA representatives are placing
top priority on employee complaints by investigating every one they receive. Author WH …
top priority on employee complaints by investigating every one they receive. Author WH …
Prof. WH Heaton
HTH Piaggio - Nature, 1941 - nature.com
… WH Heaton | Nature … WH Heaton … WH Heaton at the age of eighty–five brought to an
end a personal association with University College, Nottingham, almost from its beginning. …
end a personal association with University College, Nottingham, almost from its beginning. …