User profiles for W. E. Hoffman

Huffman WE

Professor of Economics, Iowa State University
Verified email at iastate.edu
Cited by 13361

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

…, S Hodgkinson, OM Hoffmann, WE Hofmann… - The Lancet, 2018 - thelancet.com
Background No treatment has consistently shown efficacy in slowing disability progression
in patients with secondary progressive multiple sclerosis (SPMS). We assessed the effect of …

Human capital: Education and agriculture

WE Huffman - Handbook of agricultural economics, 2001 - Elsevier
… Furthermore, as we proxy education or general intellectual achievement by schooling in
our empirical research, this has led to biased interpretations of impacts when general …

Dexmedetomidine improves neurologic outcome from incomplete ischemia in the rat. Reversal by the alpha 2-adrenergic antagonist atipamezole.

WE Hoffman, E Kochs, C Werner, C Thomas… - …, 1991 - europepmc.org
We evaluated the effect of dexmedetomidine on neurologic and histopathologic outcome
from incomplete cerebral ischemia in the rat. Anesthesia was maintained with a 25-micrograms.…

Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia

…, ML Corman, M Hajos, JF Harms, WE Hoffman… - … of Pharmacology and …, 2008 - ASPET
We have recently proposed the hypothesis that inhibition of the cyclic nucleotide … In the
present report, we describe the discovery of a new class of PDE10A inhibitors exemplified by TP-…

Fentanyl or dexmedetomidine combined with desflurane for bariatric surgery

JM Feld, WE Hoffman, MM Stechert, IW Hoffman… - Journal of clinical …, 2006 - Elsevier
We used a fentanyl infusion that has previously been shown to be effective in this … In
conclusion, we observed that dexmedetomidine treatment during open gastric bypass surgery …

Comparative pharmacokinetics and pharmacodynamics of remifentanil, its principle metabolite (GR90291) and alfentanil in dogs

…, MK James, KT Muir, WE Hoffman - … of Pharmacology and …, 1997 - ASPET
Remifentanil is an esterase-metabolized opioid developed for use in anesthesia. The
principal metabolite of remifentanil, GR90291, is considered to be less potent. This study …

The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats.

E Kochs, WE Hoffman, C Werner, C Thomas… - …, 1992 - europepmc.org
… To arrive at the top five similar articles we use a word-weighted algorithm to compare
words from the Title and Abstract of each citation. … Let us know how we are doing.How are …

Brain tissue oxygen, carbon dioxide, and pH in neurosurgical patients at risk for ischemia

WE Hoffman, FT Charbel, G Edelman - Anesthesia & Analgesia, 1996 - journals.lww.com
We hypothesized that patients with clinical evidence of ischemia would have changes in brain
… Therefore, we evaluated baseline levels of these variables, in patients with and without a …

Non-opioid analgesia improves pain relief and decreases sedation after gastric bypass surgery

…, M Beckerman, J Vincent, WE Hoffman - Canadian Journal …, 2003 - search.proquest.com
… Discussion In this study we found that a non-opioid drug combination (ketorolac, clonidine,
lidocaine, ketamine, magnesium sulfate and methylprednisolone) produced adequate …

Ketamine decreases plasma catecholamines and improves outcome from incomplete cerebral ischemia in rats.

WE Hoffman, D Pelligrino, C Werner, E Kochs… - …, 1992 - europepmc.org
We will resume services after this date. … We tested whether ketamine, an NMDA
antagonist, and NBQX, a non-NMDA antagonist, improve outcome from incomplete cerebral …