… Unpublished data of the Verri laboratory also show that diosmin treats LPS-induced
peritonitis and inflammatory pain by blocking NF-κB activation in leukocytes. Therefore, diosmin …

Pain is one of the classical signs of the inflammatory process in which sensitization of the
nociceptors is the common denominator. This sensitization causes hyperalgesia or allodynia in …

In this review, we discuss the importance of capsaicin to the current understanding of neuronal
modulation of pain and explore the mechanisms of capsaicin-induced pain. We will focus …

Background and purpose: Chemokines orchestrate neutrophil recruitment to inflammatory
foci. In the present study, we evaluated the participation of three chemokines, KC/CXCL1, MIP‐…

The flavonoid vitexin (1) is a flavone C-glycoside (apigenin-8-C-β-d-glucopyranoside) present
in several medicinal and other plants. Plant extracts containing 1 are reported to possess …

The hypernociceptive effects of cytokines [TNF-α, keratinocyte-derived chemokine (KC), and
IL-1β] and their participation in carrageenan (Cg)-induced inflammatory hypernociception in …

Vanillic acid (1) is a flavoring agent found in edible plants and fruits. It is an oxidized form of
vanillin. Phenolic compounds form a substantial part of plant foods used as antioxidants with …

Sepsis is a systemic inflammatory condition following bacterial infection with a high mortality
rate and limited therapeutic options 1 , 2 . Here we show that interleukin-33 (IL-33) reduces …

Naringenin is a flavonoid widely consumed by humans that present anti-inflammatory activity
and low toxicity. Recently, the analgesic effect of naringenin has been demonstrated in …

Neuropathic pain from injury to the peripheral and CNS represents a major health care issue.
We have investigated the role of IL‐33/IL‐33 receptor (ST2) signaling in experimental …