Chronic exposure to cigarette smoke produces profound changes in physiology that may
alter responses to perioperative interventions and contribute to perioperative morbidity. …

Abstract Effect of N-dimethyl propranolol on regional myocardial blood flow and oxygen
consumption in the canine heart.

Cervical spinal injury occurs in 2% of victims of blunt trauma; the incidence is increased if
the Glasgow Coma Scale score is less than 8 or if there is a focal neurologic deficit. …

HEALTHCARE delivery takes place 24 ha day, 7 days a week, and is colloquially termed a “24/7”
operation. Anesthesia providers are required to deliver critical around-the-clock care to …

Vascular air embolism is a potentially life-threatening event that is now encountered
routinely in the operating room and other patient care areas. The circumstances under which …

Several clinical studies suggest substantial limitations of currently available positive inotropic
substances, including beta1-adrenoceptor agonists and phosphodiesterase III inhibitors in …

A RAPIDLY growing body of evidence indicates that volatile anesthetics protect myocardium
against reversible and irreversible ischemic injury. Identifying the mechanisms by which …

Mitochondria produce metabolic energy, serve as biosensors for oxidative stress, and eventually
become effector organelles for cell death through apoptosis. The extent to which these …

IN October 1902, a “peculiar anomaly in human red blood corpuscles... came to notice in the
histologic laboratory of the Ohio State University,” Columbus, Ohio.“Examination disclosed …

THE left atrium (LA) serves three major roles that exert a profound effect on left ventricular (LV)
filling and overall cardiovascular performance. The LA is a contractile chamber that …