Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …

mRNA vaccines have been demonstrated as a powerful alternative to traditional conventional
vaccines because of their high potency, safety and efficacy, capacity for rapid clinical …

Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …

Cequa®, a unique and first-in-class preservative free cyclosporine-A (CsA) nanomicellar
topical formulation was recently approved by US FDA for treatment of dry eye disease or …

Introduction Ocular barriers hinder drug delivery and reduce drug bioavailability. This article
focuses on enhancing drug absorption across the corneal and conjunctival epithelium. Both, …

Age related macular degeneration (AMD) is one of the leading causes of visual loss and is
responsible for approximately 9% of global blindness. It is a progressive eye disorder seen in …

Hydrogels are unique biomaterials that have demonstrated tremendous potential in sustaining
drug release. Significant effort has been made to impart stimuli sensitivity and incorporate …

Aim To prepare and characterise lutein-loaded polylactide-co-glycolide–polyethylene glycol–folate
(PLGA-PEG-FOLATE) nanoparticles and evaluate enhanced uptake in SK-N-BE(2) …

Neovascular age-related macular degeneration (AMD) is characterized by an increase in
reactive oxygen species (ROS) and pro-inflammatory cytokines in the retinal pigment …

Lcn2 overexpression in metastatic breast cancer (MBC) can lead to cancer progression by
inducing the epithelial-to-mesenchymal transition and enhancing tumor angiogenesis. In this …