User profiles for Vibhudutta Awasthi
Vibhudutta AwasthiVerified email at ouhsc.edu Cited by 3447 |
[HTML][HTML] Biodegradable polymeric nanoparticles for drug delivery to solid tumors
…, M Fresta, S Bulotta, V Awasthi… - Frontiers in …, 2021 - frontiersin.org
Advances in nanotechnology have favored the development of novel colloidal formulations
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …
[HTML][HTML] Surface engineering of liposomes for stealth behavior
Liposomes are used as a delivery vehicle for drug molecules and imaging agents. The major
impetus in their biomedical applications comes from the ability to prolong their circulation …
impetus in their biomedical applications comes from the ability to prolong their circulation …
CLEFMA—An anti-proliferative curcuminoid from structure–activity relationship studies on 3, 5-bis (benzylidene)-4-piperidones
3,5-Bis(benzylidene)-4-piperidones are being advanced as synthetic analogs of curcumin
for anti-cancer and anti-inflammatory properties. We performed structure–activity relationship …
for anti-cancer and anti-inflammatory properties. We performed structure–activity relationship …
Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells
J Veeraraghavan, M Natarajan, P Lagisetty, V Awasthi… - Pancreas, 2011 - journals.lww.com
Objectives: Nuclear factor κB (NF-κB) plays an intrinsic role in promoting growth, angiogenesis,
and metastasis in pancreatic cancer (PC) and serves as a mechanism underlying …
and metastasis in pancreatic cancer (PC) and serves as a mechanism underlying …
Post-modification of preformed liposomes with novel non-phospholipid poly (ethylene glycol)-conjugated hexadecylcarbamoylmethyl hexadecanoic acid for enhanced …
We report synthesis and characterization of a novel PEG 2000 -conjugated
hexadecylcarbamoylmethyl hexadecanoate (HDAS-PEG) as a PEG-phospholipid substitute for …
hexadecylcarbamoylmethyl hexadecanoate (HDAS-PEG) as a PEG-phospholipid substitute for …
[HTML][HTML] Surface modification of liposomes by a lipopolymer targeting prostate specific membrane antigen for theranostic delivery in prostate cancer
Prostate specific membrane antigen (PSMA) is a marker for diagnosis and targeted delivery
of therapeutics to advanced/metastasized prostate cancer. We report a liposome-based …
of therapeutics to advanced/metastasized prostate cancer. We report a liposome-based …
[HTML][HTML] Homozygous expression of mutant ELOVL4 leads to seizures and death in a novel animal model of very long-chain fatty acid deficiency
Lipids are essential components of the nervous system. However, the functions of very long-chain
fatty acids (VLC-FA; ≥ 28 carbons) in the brain are unknown. The enzyme …
fatty acids (VLC-FA; ≥ 28 carbons) in the brain are unknown. The enzyme …
[HTML][HTML] Blast overpressure waves induce transient anxiety and regional changes in cerebral glucose metabolism and delayed hyperarousal in rats
…, P Tompkins, M Lerner, DJ Brackett, V Awasthi… - Frontiers in …, 2015 - frontiersin.org
Physiological alterations, anxiety, and cognitive disorders are strongly associated with blast-induced
traumatic brain injury (blast TBI), and are common symptoms in service personnel …
traumatic brain injury (blast TBI), and are common symptoms in service personnel …
Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48Cre/+-LSL-KrasG12D/+ mice
…, Q Li, RL Ritchie, S Lightfoot, A Vibhudutta… - Neoplasia, 2012 - Elsevier
Nitric oxide-releasing aspirin (NO-aspirin) represents a novel class of promising chemopreventive
agents. Unlike conventional nonsteroidal anti-inflammatory drugs, NO-aspirin seems …
agents. Unlike conventional nonsteroidal anti-inflammatory drugs, NO-aspirin seems …
[HTML][HTML] Suppression of tumor growth in mice by rationally designed pseudopeptide inhibitors of fibroblast activation protein and prolyl oligopeptidase
Tumor microenvironments (TMEs) are composed of cancer cells, fibroblasts, extracellular
matrix, microvessels, and endothelial cells. Two prolyl endopeptidases, fibroblast activation …
matrix, microvessels, and endothelial cells. Two prolyl endopeptidases, fibroblast activation …