Objective This study aimed to determine if the antioxidant N-acetylcysteine (NAC) is able to
alter peripheral and central redox capabilities in patients with Parkinson disease (PD) or …

Parkinson's disease (PD) is associated with oxidative stress and decreased nigral glutathione
(GSH), suggesting that therapies that boost GSH may have a disease‐modifying effect. …

Objective To examine the feasibility, acceptability, and preliminary effects of Hatha yoga on
oxidative stress, motor function, and non-motor symptoms among individuals with Parkinson’…

There is an increasing interest in using N-acetylcysteine (NAC) as a treatment for neurodegenerative
disorders to increase glutathione (GSH) levels and its redox status. The purpose of …

Simple and reproducible high-performance liquid chromatographic (HPLC) and gas
chromatographic—mass spectrometric (GC—MS) methods have been developed for the …

N-acetyl-l-cysteine (NAC), a well-known antioxidant, has been successfully used as adjuvant
therapy for late-stage childhood cerebral adrenoleukodystrophy (c-ALD); however, the …

Oligodendrocytic injury by oxidative stress can lead to demyelination, contributing to
neurodegeneration. We investigated the mechanisms by which an antioxidant, N-acetylcysteine (…

Purpose Although oral topiramate ( TPM ) products are widely prescribed for migraines and
epilepsy, injectable TPM is not available for human use. We have developed a solubilized …

Gaucher disease is an autosomal recessive metabolic disorder caused by mutations in GBA1,
which encodes for the lysosomal hydrolase enzyme, β-glucocerebrosidase. The resulting …

Post-traumatic epilepsy (PTE) occurs in some patients after moderate/severe traumatic
brain injury (TBI). Although there are no approved therapies to prevent epileptogenesis, …