Nociceptin/orphanin FQ peptide receptor agonist Ac-RYYRWKKKKKKK-NH2 (ZP120) induces antinatriuresis in rats by stimulation of amiloride-sensitive sodium …

USK van Deurs, N Hadrup, JS Petersen… - … of Pharmacology and …, 2009 - ASPET
The aim of the present study was to examine the mechanisms responsible for the
antinatriuretic effect of the selective, peripherally acting, nociceptin/orphanin FQ peptide (NOP) …

Extraction of cholesterol with methyl-β-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles

…, Ų Garred, F Vilhardt, B Van Deurs… - Molecular biology of …, 1999 - Am Soc Cell Biol
The importance of cholesterol for endocytosis has been investigated in HEp-2 and other cell
lines by using methyl-β-cyclodextrin (MβCD) to selectively extract cholesterol from the …

[HTML][HTML] Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding

…, P Thomsen, K Sandvig, B Van Deurs - Journal of Biological …, 2002 - ASBMB
Cholesterol depletion has been shown to increase mitogen-activated protein kinase activation
in response to stimulation with epidermal growth factor (EGF) (Furuchi, T., and Anderson, …

Caveolae are highly immobile plasma membrane microdomains, which are not involved in constitutive endocytic trafficking

…, K Roepstorff, M Stahlhut, B van Deurs - Molecular biology of …, 2002 - Am Soc Cell Biol
To investigate whether caveolae are involved in constitutive endocytic trafficking, we expressed
N- and C- terminally green fluorescent protein (GFP)-tagged caveolin- 1 fusion proteins …

Association with membrane protrusions makes ErbB2 an internalization-resistant receptor

…, M Lerdrup, B van Deurs - Molecular biology of the …, 2004 - Am Soc Cell Biol
… We thank Ulla Hjortenberg and Mette Ohlsen for expert technical assistance and Keld
Ottesen for photographical work. We thank Kirstine Roepstorff, Frederik Vilhardt, and Michael …

Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way

…, M Grandal, B van Deurs - Journal of cell …, 2006 - journals.biologists.com
… confocal microscopical assay allowing quantitative analysis of ErbB2 internalization in
cell populations, we show that whereas ErbB2 is resistant to internalization in untreated SK-BR-3 …

EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes

…, MW Pedersen, BM Willumsen, B van Deurs… - …, 2007 - academic.oup.com
… Bo van Deurs … We greatly appreciate the skilled work of Mette Ohlsen, Ulla Hjortenberg
and Izabella Rasmussen. We thank Nina Pedersen, Mads Lerdrup, Anette Hommelgaard, …

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus

…, AM Hommelgaard, B van Deurs - Molecular biology of …, 2007 - Am Soc Cell Biol
… We appreciate the skilled technical assistance offered by Ulla Hjortenberg, Mette Ohlsen,
and Izabela Rasmussen. This study was supported by grants from the Danish Cancer Society, …

Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor

…, PJ Courtoy, K Sandvig, B Van Deurs - Molecular biology of …, 2000 - Am Soc Cell Biol
… PN was working in the van Deurs laboratory with support from the European Community. …
PN was working in the van Deurs laboratory with support from the European Community. …

Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells

A Llorente, B van Deurs, K Sandvig - European journal of cell biology, 2007 - Elsevier
… We thank Ulla Hjortenberg and Mette Ohlsen for their excellent technical assistance. The
present study was supported by The Norwegian Cancer Society, The Research Council of …