Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits
Objectives To quantify and compare potential benefits (subjective reports of sleep variables)
and risks (adverse events and morning-after psychomotor impairment) of short term …
and risks (adverse events and morning-after psychomotor impairment) of short term …
The role of the brain reward system in depression
CA Naranjo, LK Tremblay, UE Busto - Progress in Neuro …, 2001 - Elsevier
The goal of this review is to familiarize the reader about the potential involvement of the
brain reward system (BRS) in symptoms of Major Depressive Disorder (MDD). The authors …
brain reward system (BRS) in symptoms of Major Depressive Disorder (MDD). The authors …
Functional neuroanatomical substrates of altered reward processing in major depressive disorder revealed by a dopaminergic probe
…, HS Mayberg, S Hevenor, UE Busto - Archives of general …, 2005 - jamanetwork.com
… UE Probing the brain reward system in major depressive … UE The role of the brain reward
system in depression. … UE Probing the brain reward system in major depressive disorder: …
system in depression. … UE Probing the brain reward system in major depressive disorder: …
Probing brain reward system function in major depressive disorder: altered response to dextroamphetamine
…, L Cardenas, N Herrmann, UE Busto - Archives of general …, 2002 - jamanetwork.com
Background The state of the brain reward system in major depressive disorder was
assessed with dextroamphetamine, which probes the release of dopamine within the …
assessed with dextroamphetamine, which probes the release of dopamine within the …
CYP2D6 phenotype determines the metabolic conversion of hydrocodone to hydromorphone
…, SW Cheung, HL Kaplan, UE Busto… - Clinical …, 1993 - Wiley Online Library
The contribution of cytochrome P450 2D6 (CYP2D6) to the formation of hydrocodone's active
metabolite, hydromorphone, was examined in vitro and in vivo. Human liver microsomes …
metabolite, hydromorphone, was examined in vitro and in vivo. Human liver microsomes …
A clinical scale to assess benzodiazepine withdrawal
UE Busto, K Sykora, EM Sellers - Journal of clinical …, 1989 - journals.lww.com
The objective, sensitive, and reliable quantitation of withdrawal symptoms is essential to
assess physical dependence on drugs. Data collected from 23 patients abusing high doses of …
assess physical dependence on drugs. Data collected from 23 patients abusing high doses of …
Methylphenidate for the treatment of apathy in Alzheimer disease: prediction of response using dextroamphetamine challenge
…, SE Black, M Ryan, BA Liu, UE Busto… - Journal of clinical …, 2008 - journals.lww.com
Apathy is a common behavioral symptom of Alzheimer's disease (AD), being present in up
to 70% of patients. Apathy in AD and non-AD populations has been associated with …
to 70% of patients. Apathy in AD and non-AD populations has been associated with …
Characteristics of dependent and nondependent regular users of codeine
BA Sproule, UE Busto, G Somer… - Journal of Clinical …, 1999 - journals.lww.com
Although codeine is a widely used medication, the problems of codeine abuse and dependence
have not been well-studied. This study characterized regular codeine users (using at …
have not been well-studied. This study characterized regular codeine users (using at …
Effects of 2-week treatment with temazepam and diphenhydramine in elderly insomniacs: a randomized, placebo-controlled trial
…, BA Sproule, N Herrmann, UE Busto - Journal of clinical …, 2008 - journals.lww.com
A randomized, controlled, crossover clinical study compared 14-night treatment with 15 mg
temazepam, 50 mg diphenhydramine, and placebo in elderly individuals with insomnia (…
temazepam, 50 mg diphenhydramine, and placebo in elderly individuals with insomnia (…
The efficacy, safety and tolerability of antidepressants in late life depression: a meta-analysis
…, N Herrmann, TR Einarson, UE Busto… - Journal of affective …, 1997 - Elsevier
Background: To determine the efficacy, safety and tolerability of antidepressants in
depressed elderly patients. Methods: Search for randomized controlled double-blind studies …
depressed elderly patients. Methods: Search for randomized controlled double-blind studies …