[HTML][HTML] Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-κB and free radical in proximal tubular cells

…, A Hosokawa, H Yamato, T Muraki, T Yoshioka - Kidney international, 2003 - Elsevier
… Author links open overlay panel Masaru Motojima , Atsuko Hosokawa , Hideyuki Yamato
, Takamura Muraki , Toshimasa YoshiokaYoshiokaYoshioka

Reduced activity of antioxidant enzymes underlies contrast media-induced renal injury in volume depletion

T Yoshioka, A Fogo, JK Beckman - Kidney international, 1992 - Elsevier
Reduced activity of renal antioxidant enzymes underlies contrast media-induced renal injury
in volume depletion. Oxidant-mediated renal injury has been suggested as an important …

Role of abnormally high transmural pressure in the permselectivity defect of glomerular capillary wall: a study in early passive Heymann nephritis.

T Yoshioka, HG Rennke, DJ Salant, WM Deen… - Circulation …, 1987 - Am Heart Assoc
To explore the mechanism of glomerular permselectivity defect in passive Heymann nephritis,
an experimental model of human membranous glomerulopathy, Munich-Wistar rats were …

Plasmapheresis as the sole therapy for rapidly progressive Henoch-Schönlein purpura nephritis in children

…, K Ito, T Konomoto, H Kawaguchi, T Yoshioka… - American journal of …, 1999 - Elsevier
To clarify the therapeutic role of plasmapheresis (PP) for patients with Henoch-Schönlein
purpura (HSP) nephritis, the clinical courses of nine children with a rapidly progressive type of …

Uremic toxins overload accelerates renal damage in a rat model of chronic renal failure

…, M Watanabe, K Ueda, H Yamato, T Yoshioka… - Nephron experimental …, 2003 - karger.com
Uremic toxins have been suggested to promote progression of chronic renal failure by
damaging tubular cells. Previous in vitro studies have indicated that some uremic toxins induce …

Uraemic toxins induce proximal tubular injury via organic anion transporter 1‐mediated uptake

…, H Yamato, T Muraki, T Yoshioka - British journal of …, 2002 - Wiley Online Library
A direct effect of uraemic toxins in promoting progression of chronic renal disease has not
been established. In this study, we investigated the toxic effects of organic anions which …

Team-based learning, a learning strategy for clinical reasoning, in students with problem-based learning tutorial experiences

…, S Nunoda, S Sugihara, T Yoshioka - The Tohoku Journal of …, 2012 - jstage.jst.go.jp
Acquiring clinical reasoning skills in lectures may be difficult, but it can be learnt through
problem-solving in the context of clinical practice. Problem finding and solving are skills …

Blood pressure-independent effect of angiotensin inhibition on vascular lesions of chronic renal failure

Y Kakinuma, T Kawamura, T Bills, T Yoshioka… - Kidney international, 1992 - Elsevier
Blood pressure-independent effect of angiotensin inhibition on vascular lesions of chronic
renal failure. Previous studies in experimental models of progressive renal failure have shown …

Glucocorticoid activates glomerular antioxidant enzymes and protects glomeruli from oxidant injuries

T Kawamura, T Yoshioka, T Bills, A Fogo, I Ichikawa - Kidney international, 1991 - Elsevier
Glucocorticoid activates glomerular antioxidant enzymes and protects glomeruli from
oxidant injuries. We examined the effect of glucocorticoid on intrinsic glomerular antioxidant …

Role for angiotensin II in an overt functional proteinuria

T Yoshioka, T Mitarai, V Kon, WM Deen, HG Rennke… - Kidney international, 1986 - Elsevier
Role for angiotensin II in an overt functional proteinuria. A partial renal vein constriction (RVC)
was induced acutely in Munich–Wistar rats. RVC caused a marked reduction in …