Food products containing cannabis extract (edibles) have emerged as a popular and
lucrative facet of the legalized market for both recreational and medicinal cannabis. The many …

Diversion of synthetic cannabinoids for abuse began in the early 2000s. Despite legislation
banning compounds currently on the drug market, illicit manufacturers continue to release …

Synthetic indole-derived cannabinoids have become commonly used recreational drugs
and continue to be abused despite their adverse consequences. As compounds that were …

Synthetic cannabinoids are a class of novel psychoactive substances that exhibit high
affinity at the cannabinoid type-1 (CB 1 ) receptor and produce effects similar to those of Δ-9-…

Use of cannabidiol (CBD) in humans has increased considerably in recent years. While
currently available studies suggest that CBD is relatively safe for human consumption, data from …

An important data gap in determining a safe level of cannabidiol (CBD) intake for consumer
use is determination of CBD's potential to cause reproductive or developmental toxicity. We …

Background Women report greater sensitivity to the subjective effects of Δ 9 -tetrahydrocannabinol
(THC). Similarly, female rodents tend to be more sensitive to some pharmacological …

Anecdotal reports suggest that abused synthetic cannabinoids produce cannabis-like “highs,”
but some of their effects may also differ from traditional cannabinoids such as Δ 9 -…

CUMYL-PICA [1-pentyl-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide] and 5F-CUMYL-PICA
[1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide] are recently …

Cannabis edibles are becoming more common in an increasingly diverse population of users,
and the impact of first pass metabolism on cannabis's pharmacological profile across age …