[PDF][PDF] Subclasses of angiotensin II binding sites and their functional significance.
DT Dudley, RL Panek, TC Major, GH Lu… - Molecular …, 1990 - Citeseer
Specific binding sites for angiotensin II were identified in the rabbit adrenal gland and uterus
and in the rat liver and were divided into two subclasses based on inhibition by nonpeptide …
and in the rat liver and were divided into two subclasses based on inhibition by nonpeptide …
Measurement of tear glucose levels with amperometric glucose biosensor/capillary tube configuration
An amperometric needle-type electrochemical glucose sensor intended for tear glucose
measurements is described and employed in conjunction with a 0.84 mm id capillary tube to …
measurements is described and employed in conjunction with a 0.84 mm id capillary tube to …
Long-term nitric oxide release and elevated temperature stability with S-nitroso-N-acetylpenicillamine (SNAP)-doped Elast-eon E2As polymer
EJ Brisbois, H Handa, TC Major, RH Bartlett… - Biomaterials, 2013 - Elsevier
Nitric oxide (NO) is known to be a potent inhibitor of platelet activation and adhesion. Healthy
endothelial cells that line the inner walls of all blood vessels exhibit a NO flux of 0.5–4 × 10 …
endothelial cells that line the inner walls of all blood vessels exhibit a NO flux of 0.5–4 × 10 …
Structure−Activity Relationships for a Novel Series of Pyrido[2,3-d]pyrimidine Tyrosine Kinase Inhibitors
…, HDH Showalter, RL Panek, TC Major… - Journal of medicinal …, 1997 - ACS Publications
Screening of a compound library for inhibitors of the fibroblast growth factor (FGFr) and
platelet-derived growth factor (PDGFr) receptor tyrosine kinases led to the development of a …
platelet-derived growth factor (PDGFr) receptor tyrosine kinases led to the development of a …
The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer
TC Major, DO Brant, MM Reynolds, RH Bartlett… - Biomaterials, 2010 - Elsevier
Nitric oxide (NO) has been shown to reduce thrombogenicity by decreasing platelet and
monocyte activation by the surface glycoprotein, P-selectin and the integrin, CD11b, respectively…
monocyte activation by the surface glycoprotein, P-selectin and the integrin, CD11b, respectively…
2-Substituted Aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer …
…, DJ Dykes, RL Panek, GH Lu, TC Major… - Journal of medicinal …, 1998 - ACS Publications
While engaged in therapeutic intervention against a number of proliferative diseases, we
have discovered the 2-aminopyrido[2,3-d]pyrimidin-7(8H)-ones as a novel class of potent, …
have discovered the 2-aminopyrido[2,3-d]pyrimidin-7(8H)-ones as a novel class of potent, …
The hemocompatibility of a nitric oxide generating polymer that catalyzes S-nitrosothiol decomposition in an extracorporeal circulation model
TC Major, DO Brant, CP Burney, KA Amoako… - Biomaterials, 2011 - Elsevier
Nitric oxide (NO) generating (NOGen) materials have been shown previously to create
localized increases in NO concentration by the catalytic decomposition of blood S-nitrosothiols (…
localized increases in NO concentration by the catalytic decomposition of blood S-nitrosothiols (…
Origin of Long-Term Storage Stability and Nitric Oxide Release Behavior of CarboSil Polymer Doped with S-Nitroso-N-acetyl-d-penicillamine
The prolonged and localized delivery of nitric oxide (NO), a potent antithrombotic and
antimicrobial agent, has many potential biomedical applications. In this work, the origin of the long-…
antimicrobial agent, has many potential biomedical applications. In this work, the origin of the long-…
Reduction in thrombosis and bacterial adhesion with 7 day implantation of S-nitroso-N-acetylpenicillamine (SNAP)-doped Elast-eon E2As catheters in sheep
EJ Brisbois, RP Davis, AM Jones, TC Major… - Journal of Materials …, 2015 - pubs.rsc.org
Thrombosis and infection are two common problems associated with blood-contacting medical
devices such as catheters. Nitric oxide (NO) is known to be a potent antimicrobial agent …
devices such as catheters. Nitric oxide (NO) is known to be a potent antimicrobial agent …
Extracellular matrix metalloproteinase inducer (EMMPRIN) is induced upon monocyte differentiation and is expressed in human atheroma
TC Major, L Liang, X Lu, W Rosebury… - … , and vascular biology, 2002 - Am Heart Assoc
Objective— Because extracellular matrix metalloproteinase inducer (EMMPRIN), a tumor
cell–derived protein, induces matrix metalloproteinases (MMPs) in fibroblasts and because …
cell–derived protein, induces matrix metalloproteinases (MMPs) in fibroblasts and because …