Does rubidium-82 PET have superior accuracy to SPECT perfusion imaging for the diagnosis of obstructive coronary disease? A systematic review and meta-analysis
BA Mc Ardle, TF Dowsley, RA Dekemp… - Journal of the American …, 2012 - jacc.org
Objectives : The purpose of this study was to evaluate the accuracy of rubidium (Rb)-82
positron emission tomography (PET) for the diagnosis of obstructive coronary artery disease (…
positron emission tomography (PET) for the diagnosis of obstructive coronary artery disease (…
Diastolic dysfunction in patients with end-stage liver disease is associated with development of heart failure early after liver transplantation
TF Dowsley, DB Bayne, AN Langnas, I Dumitru… - …, 2012 - journals.lww.com
… Henriksen JH, Fuglsang S, Bendtsen F, et al.. Cirrhotic cardiomyopathy: prolonged QTc-interval
and dyssynchronic electrical and mechanical systole in cirrhosis. Ugeskr Laeger 2004; 166 …
and dyssynchronic electrical and mechanical systole in cirrhosis. Ugeskr Laeger 2004; 166 …
Cardiovascular Implantable Electronic Device Infection in Patients with Staphylococcus aureus Bacteremia
DZ Uslan, TF Dowsley, MR Sohail… - Pacing and clinical …, 2010 - Wiley Online Library
Background: Staphylococcus aureus bacteremia (SAB) in patients with cardiovascular
implantable electronic devices (CIED), including permanent pacemakers (PPMs) and implantable …
implantable electronic devices (CIED), including permanent pacemakers (PPMs) and implantable …
Cardiac PET: metabolic and functional imaging of the myocardium
B Mc Ardle, TF Dowsley, MS Cocker, H Ohira… - Seminars in nuclear …, 2013 - Elsevier
Cardiac PET has evolved over the past 30 years to gain wider acceptance as a valuable
modality for a variety of cardiac conditions. Wider availability of scanners as well as changes in …
modality for a variety of cardiac conditions. Wider availability of scanners as well as changes in …
Complementary pre-operative risk assessment using coronary computed tomography angiography and nuclear myocardial perfusion imaging in non-cardiac surgery …
TF Dowsley, T Sheth, BJW Chow - Journal of Nuclear Cardiology, 2020 - Springer
Background The incremental value and optimal utilization of non-invasive testing for prediction
of peri-operative cardiac events during non-cardiac surgery are not clear. Methods A sub-…
of peri-operative cardiac events during non-cardiac surgery are not clear. Methods A sub-…
Reaction of glutathione with the electrophilic metabolites of 1, 1-dichloroethylene
TF Dowsley, PG Forkert, LA Benesch… - Chemico-biological …, 1995 - Elsevier
1,1-Dichloroethylene (DCE) requires cytochrome P450-catalyzed bioactivation to
electrophilic metabolites (1,1-dichloroethylene oxide, 2-chloroacetyl chloride and 2,2-…
electrophilic metabolites (1,1-dichloroethylene oxide, 2-chloroacetyl chloride and 2,2-…
Cytochrome P-450-dependent bioactivation of 1, 1-dichloroethylene to a reactive epoxide in human lung and liver microsomes
TF Dowsley, K Reid, D Petsikas, JB Ulreich… - … of Pharmacology and …, 1999 - ASPET
We investigated the cytochrome P-450-dependent metabolism of 1,1-dichloroethylene (DCE)
by human lung and liver microsomes and compared the results from analogous …
by human lung and liver microsomes and compared the results from analogous …
CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates
TF Dowsley, JB Ulreich, JL Bolton, SS Park… - Toxicology and applied …, 1996 - Elsevier
We investigated the cytochrome P450-dependent metabolism of 1,1-dichloroethylene (DCE)
in murine lung microsomal incubations. The metabolites were identified as their glutathione …
in murine lung microsomal incubations. The metabolites were identified as their glutathione …
Assessment of Cardiac Computed TomographyMyocardial Perfusion Imaging–Promise and Challenges–
G Dwivedi, TF Dowsley, BJW Chow - Circulation Journal, 2012 - jstage.jst.go.jp
545 CT Perfusion tended to include functional assessment of the myocardium not only at
rest but also during stress. 21–25 Simultaneous anatomical and functional assessment …
rest but also during stress. 21–25 Simultaneous anatomical and functional assessment …
Immunochemical assay for recognition of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene-epoxide
PG Forkert, KS Collins, TF Dowsley, GM Ross - Journal of Pharmacology …, 1997 - ASPET
Cytotoxicities induced by 1,1-dichloroethylene (DCE) are ascribed to cytochrome P450-dependent
metabolism to an epoxide. Conjugation of the DCE-epoxide with glutathione (GSH) …
metabolism to an epoxide. Conjugation of the DCE-epoxide with glutathione (GSH) …