Does rubidium-82 PET have superior accuracy to SPECT perfusion imaging for the diagnosis of obstructive coronary disease? A systematic review and meta-analysis

BA Mc Ardle, TF Dowsley, RA Dekemp… - Journal of the American …, 2012 - jacc.org
Objectives : The purpose of this study was to evaluate the accuracy of rubidium (Rb)-82
positron emission tomography (PET) for the diagnosis of obstructive coronary artery disease (…

Diastolic dysfunction in patients with end-stage liver disease is associated with development of heart failure early after liver transplantation

TF Dowsley, DB Bayne, AN Langnas, I Dumitru… - …, 2012 - journals.lww.com
… Henriksen JH, Fuglsang S, Bendtsen F, et al.. Cirrhotic cardiomyopathy: prolonged QTc-interval
and dyssynchronic electrical and mechanical systole in cirrhosis. Ugeskr Laeger 2004; 166 …

Cardiovascular Implantable Electronic Device Infection in Patients with Staphylococcus aureus Bacteremia

DZ Uslan, TF Dowsley, MR Sohail… - Pacing and clinical …, 2010 - Wiley Online Library
Background: Staphylococcus aureus bacteremia (SAB) in patients with cardiovascular
implantable electronic devices (CIED), including permanent pacemakers (PPMs) and implantable …

Cardiac PET: metabolic and functional imaging of the myocardium

B Mc Ardle, TF Dowsley, MS Cocker, H Ohira… - Seminars in nuclear …, 2013 - Elsevier
Cardiac PET has evolved over the past 30 years to gain wider acceptance as a valuable
modality for a variety of cardiac conditions. Wider availability of scanners as well as changes in …

Complementary pre-operative risk assessment using coronary computed tomography angiography and nuclear myocardial perfusion imaging in non-cardiac surgery …

TF Dowsley, T Sheth, BJW Chow - Journal of Nuclear Cardiology, 2020 - Springer
Background The incremental value and optimal utilization of non-invasive testing for prediction
of peri-operative cardiac events during non-cardiac surgery are not clear. Methods A sub-…

Reaction of glutathione with the electrophilic metabolites of 1, 1-dichloroethylene

TF Dowsley, PG Forkert, LA Benesch… - Chemico-biological …, 1995 - Elsevier
1,1-Dichloroethylene (DCE) requires cytochrome P450-catalyzed bioactivation to
electrophilic metabolites (1,1-dichloroethylene oxide, 2-chloroacetyl chloride and 2,2-…

Cytochrome P-450-dependent bioactivation of 1, 1-dichloroethylene to a reactive epoxide in human lung and liver microsomes

TF Dowsley, K Reid, D Petsikas, JB Ulreich… - … of Pharmacology and …, 1999 - ASPET
We investigated the cytochrome P-450-dependent metabolism of 1,1-dichloroethylene (DCE)
by human lung and liver microsomes and compared the results from analogous …

CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates

TF Dowsley, JB Ulreich, JL Bolton, SS Park… - Toxicology and applied …, 1996 - Elsevier
We investigated the cytochrome P450-dependent metabolism of 1,1-dichloroethylene (DCE)
in murine lung microsomal incubations. The metabolites were identified as their glutathione …

Assessment of Cardiac Computed TomographyMyocardial Perfusion Imaging–Promise and Challenges–

G Dwivedi, TF Dowsley, BJW Chow - Circulation Journal, 2012 - jstage.jst.go.jp
545 CT Perfusion tended to include functional assessment of the myocardium not only at
rest but also during stress. 21–25 Simultaneous anatomical and functional assessment …

Immunochemical assay for recognition of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene-epoxide

PG Forkert, KS Collins, TF Dowsley, GM Ross - Journal of Pharmacology …, 1997 - ASPET
Cytotoxicities induced by 1,1-dichloroethylene (DCE) are ascribed to cytochrome P450-dependent
metabolism to an epoxide. Conjugation of the DCE-epoxide with glutathione (GSH) …