Acquiring clinical reasoning skills in lectures may be difficult, but it can be learnt through
problem-solving in the context of clinical practice. Problem finding and solving are skills …

Anti‐inflammatory effects of cyclic AMP elevating agents were examined in a mouse model
of lipopolysaccharide (LPS)‐induced microvascular permeability change. Vascular …

Background: Adaptation to problem-based learning (PBL) is a difficult process for high school
graduates who are not used to self-directed learning, especially in the freshmen year of …

Introduction: In this study, we compared the choice of medical specialty and subspecialty
interest among problem-based-learning (PBL) graduates and non-PBL graduates. Materials …

The effect of heat shock protein (hsp) induction on lipopolysaccharide (LPS)-induced
increase in vascular permeability was studied in mice as a model of inflammatory mediator-…

The anti-inflammatory effect of FR167653 (1-[7-(4-fluorophenyl)-1,2,3,4-tetrahydro-8-(4-pyridyl)pyrazolo[5,1-c][1,2,4]triazin-2-yl]-2-phenylethanedione
sulfate monohydrate), a p38 …

The relationship between the pharmacokinetic properties and the analgesic effect of
indomethacin (IDM) was evaluated on a carrageenin-induced inflammation model in the rat. Rats …

This study aimed to investigate the behavior of an endogenous β-endorphin (β-EP) in the
brain after subcutaneous (sc) injection of carrageenin or intravenous (iv) injection of …

In order to assess quantitatively the pharmacodynamic process of pentazocine (PTZ), time
courses of its plasma concentration and of the occupation of specific opioid receptors in the …

Many medical schools adopted PBL tutorial as a medical education strategy1). The educational
outcome of PBL has been discussed in the variety of settings yielding different results2, 3…