[HTML][HTML] Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial
…, J Booth, N McInnes, A Smith, I Stanton, T Tazzeo… - The Lancet, 2017 - thelancet.com
Background Pregnant women with type 1 diabetes are a high-risk population who are
recommended to strive for optimal glucose control, but neonatal outcomes attributed to maternal …
recommended to strive for optimal glucose control, but neonatal outcomes attributed to maternal …
KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase
LJ Janssen, T Tazzeo, J Zuo… - American Journal of …, 2004 - journals.physiology.org
Airway smooth muscle (ASM) cells express voltage-dependent Ca 2+ channels, primarily of
the L-subtype. These may play a role in excitation-contraction coupling of ASM, although …
the L-subtype. These may play a role in excitation-contraction coupling of ASM, although …
Acute response of airway muscle to extreme temperature includes disruption of actin–myosin interaction
P Dyrda, T Tazzeo, L DoHarris, B Nilius… - American journal of …, 2011 - atsjournals.org
Despite the emerging use of bronchial thermoplasty in asthma therapy, the response of
airway smooth muscle (ASM) to extreme temperatures is unknown. We investigated the …
airway smooth muscle (ASM) to extreme temperatures is unknown. We investigated the …
The NADPH oxidase inhibitor diphenyleneiodonium is also a potent inhibitor of cholinesterases and the internal Ca2+ pump
T Tazzeo, F Worek, LJ Janssen - British journal of …, 2009 - Wiley Online Library
Background and purpose: Diphenyleneiodonium (DPI) is often used as an NADPH oxidase
inhibitor, but is increasingly being found to have unrelated side effects. We investigated its …
inhibitor, but is increasingly being found to have unrelated side effects. We investigated its …
Caffeine relaxes smooth muscle through actin depolymerization
T Tazzeo, G Bates, HN Roman… - … of Physiology-Lung …, 2012 - journals.physiology.org
Caffeine is sometimes used in cell physiological studies to release internally stored Ca 2+ .
We obtained evidence that caffeine may also act through a different mechanism that has not …
We obtained evidence that caffeine may also act through a different mechanism that has not …
Involvement of TP and EP3 receptors in vasoconstrictor responses to isoprostanes in pulmonary vasculature
LJ Janssen, T Tazzeo - Journal of Pharmacology and Experimental …, 2002 - ASPET
Although isoprostanes generally act on smooth muscle via TXA 2 -selective prostanoid
receptors (TPs), some suggest other prostanoid receptors or possibly even a novel isoprostane-…
receptors (TPs), some suggest other prostanoid receptors or possibly even a novel isoprostane-…
Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles
…, J Wattie, H Lu-Chao, T Tazzeo - Journal of Applied …, 2001 - journals.physiology.org
We investigated the mechanisms underlying muscarinic excitation-contraction coupling in
canine airway smooth muscle using organ bath, fura 2 fluorimetric, and patch-clamp …
canine airway smooth muscle using organ bath, fura 2 fluorimetric, and patch-clamp …
Enhanced Myosin Phosphatase and Ca2+-Uptake Mediate Adrenergic Relaxation of Airway Smooth Muscle
LJ Janssen, T Tazzeo, J Zuo - American journal of respiratory cell …, 2004 - atsjournals.org
We examined the mechanisms underlying relaxations evoked by isoproterenol (Iso) in isolated
porcine, bovine, or human tracheal and bronchial tissues (TSM and BSM, respectively). …
porcine, bovine, or human tracheal and bronchial tissues (TSM and BSM, respectively). …
Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling
C Liu, T Tazzeo, LJ Janssen - American Journal of …, 2006 - journals.physiology.org
We previously reported the ability of isoprostanes to induce airway hyperresponsiveness (AHR).
In this study, we examined the signaling mechanisms underlying that phenomenon with …
In this study, we examined the signaling mechanisms underlying that phenomenon with …
Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle
T Tazzeo, J Miller, LJ Janssen - British journal of pharmacology, 2003 - Wiley Online Library
We investigated the effects of five different isoprostanes (8‐iso PGE 1 , 8‐iso PGE 2 , 8‐iso
PGF 1α , 8‐iso PGF 2α and 8‐iso PGF 2β ) on vasomotor tone in human and porcine …
PGF 1α , 8‐iso PGF 2α and 8‐iso PGF 2β ) on vasomotor tone in human and porcine …