Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

…, T Santa, N Okiyama, T Fukushima… - Biomedical …, 2001 - Wiley Online Library
Fluorogenic and fluorescent labeling reagents having a benzofurazan (2,1,3‐benzoxadiazole)
skeleton such as 4‐fluoro‐7‐nitro‐2,1,3‐benzoxadiazole (NBD‐F), 4‐N,N‐…

Derivatization reagents in liquid chromatography/electrospray ionization tandem mass spectrometry

T Santa - Biomedical Chromatography, 2011 - Wiley Online Library
… Girard's reagent P [1-(carboxymethyl)pyridium chloride hydrazide; Gir P] and Girard's reagent
T [(carboxymethyl)trimethylammonium chloride hydrazide; Gir T] are reagents that possess …

Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis

…, T Santa, Y Shintani, H Fujie, H Miyoshi, T Tsutsumi… - Cancer research, 2001 - AACR
The mechanism of hepatocarcinogenesis in hepatitis C virus (HCV) infection is still
undefined. One possibility is the involvement of oxidative stress, which can produce genetic …

Recent progress in derivatization methods for LC and CE analysis

T Fukushima, N Usui, T Santa, K Imai - Journal of pharmaceutical and …, 2003 - Elsevier
… -SH [81] (Scheme 2) were theoretically designed and synthesized on the basis of the
fluorescence characteristics and Hammett substituent constants or PM3 calculation of the S 1 –T 2 …

Quantitative evaluation of the therapeutic effects of antibiotics using silkworms infected with human pathogenic microorganisms

…, H Kusuhara, T Santa… - Antimicrobial agents …, 2004 - Am Soc Microbiol
The injection of bacteria (Staphylococcus aureus, Stenotrophomonas maltophilia) or true
fungi (Candida albicans, Candida tropicalis) that are pathogenic to humans into the silkworm …

Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure possible involvement of nitric …

…, K Iijima, M Eto, T Kojima, E Ohga, T Santa… - Circulation …, 2005 - jstage.jst.go.jp
Background Asymmetric NG, NG-dimethylarginine (ADMA) is an endogenous inhibitor of
endothelial nitric oxide (NO) synthase and its plasma concentration is elevated in patients with …

Regional distribution and postnatal changes of D-amino acids in rat brain

…, H Homma, Y Takigawa, T Fukushima, T Santa… - … et Biophysica Acta (BBA …, 1997 - Elsevier
Regional distribution of d-amino acids in rat brain was studied by the modified highly sensitive
analytical method which was previously developed. The method includes fluorogenic …

Pharmacokinetic profile of glycyrrhizin in healthy volunteers by a new high‐performance liquid chromatographic method

Y Yamamura, J Kawakami, T Santa… - Journal of …, 1992 - Wiley Online Library
… YOSHIKAZU YAMAMURA*X, JUNICHI KAWAKAMI', TOMOFUMI SANTA*, HAJIME KOTAKI*…
Pharmacokinetic Analysis-The concentrations of 1 in plasma (C,) at time t after intravenous …

d-Aspartate Uptake into Cultured Rat Pinealocytes and the Concomitant Effect onl-Aspartate Levels and Melatonin Secretion

…, JA Lee, T Fukushima, T Santa, T Iwatsubo… - Biochemical and …, 1998 - Elsevier
Significant amounts of D-aspartate (Asp) are found in mammalian tissues and D-Asp is
presumed to play some significant, but as yet undefined physiological role. However, it is not …

Effects of the substituent groups at the 4-and 7-positions on the fluorescence characteristics of benzofurazan compounds

S Uchiyama, T Santa, T Fukushima… - Journal of the Chemical …, 1998 - pubs.rsc.org
To develop new fluorogenic reagents having the benzofurazan structure, we investigated the
effects of the substituent groups at the 4- and 7-positions of the benzofurazan skeleton on …