[HTML][HTML] The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza

…, R Iwamoto, T Watanebe, S Sakabe, T Daidoji… - Cell, 2013 - cell.com
Influenza A viruses are a major cause of mortality. Given the potential for future lethal pandemics,
effective drugs are needed for the treatment of severe influenza such as that caused by …

Survival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus on human skin: importance of hand hygiene in coronavirus disease …

…, T Yoshida, R Bandou, T Daidoji… - Clinical Infectious …, 2021 - academic.oup.com
Background The stability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
on human skin remains unknown, considering the hazards of viral exposure to humans. …

[HTML][HTML] Differences in environmental stability among SARS-CoV-2 variants of concern: both omicron BA. 1 and BA. 2 have higher stability

…, T Yoshida, R Bandou, T Daidoji, T Nakaya - Clinical Microbiology …, 2022 - Elsevier
… The values of residual viral titre on surfaces were evaluated with Student's t-test, and the
magnitudes with P < 0.05 were considered significant. ∗P < 0.05 (versus the Wuhan strain). † P …

Novel type II transmembrane serine proteases, MSPL and TMPRSS13, Proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic …

…, M Yano, M Ohuchi, T Daidoji, T Nakaya… - Journal of …, 2010 - Am Soc Microbiol
Host cellular proteases induce influenza virus entry into cells by cleaving the viral surface
envelope glycoprotein hemagglutinin (HA). However, details on the cellular proteases …

[HTML][HTML] Disinfectant effectiveness against SARS-CoV-2 and influenza viruses present on human skin: model-based evaluation

…, T Yoshida, T Daidoji, Y Naito, Y Itoh, T Nakaya - Clinical Microbiology …, 2021 - Elsevier
Objectives Disinfection effectiveness against severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) on human skin remains unclear because of the hazards of viral exposure. …

[HTML][HTML] Irradiation by ultraviolet light-emitting diodes inactivates influenza a viruses by inhibiting replication and transcription of viral RNA in host cells

…, T Wada, M Okamoto, H Ito, K Yoshida, T Daidoji… - … of Photochemistry and …, 2018 - Elsevier
Influenza A viruses (IAVs) pose a serious global threat to humans and their livestock, especially
poultry and pigs. This study aimed to investigate how to inactivate IAVs by using different …

[HTML][HTML] ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner

…, T Ono, S Ushiba, S Nakakita, T Daidoji… - Communications …, 2022 - nature.com
… hACE2 has seven canonical sequons for N-glycosylation (NXS/T, where X is any amino
acid except P; Fig. 1a) 26,28 . Among the predicted N-glycosylation sites, in this study we …

Mechanism of human influenza virus RNA persistence and virion survival in feces: mucus protects virions from acid and digestive juices

R Hirose, T Nakaya, Y Naito, T Daidoji… - The Journal of …, 2017 - academic.oup.com
Although viral RNA or infectious virions have been detected in the feces of individuals
infected with human influenza A and B viruses (IAV/IBV), the mechanism of viral survival in the …

[HTML][HTML] Novel polymerase gene mutations for human adaptation in clinical isolates of avian H5N1 influenza viruses

…, T Daidoji, MS Ibrahim, EM El-Gendy, T Takagi… - PLoS …, 2016 - journals.plos.org
A major determinant in the change of the avian influenza virus host range to humans is the
E627K substitution in the PB2 polymerase protein. However, the polymerase activity of avian …

Situations leading to reduced effectiveness of current hand hygiene against infectious mucus from influenza virus-infected patients

R Hirose, T Nakaya, Y Naito, T Daidoji, R Bandou… - MSphere, 2019 - Am Soc Microbiol
… from the minimum value of 0.05 midpoint temperature (T m −1 ). The maximum gradient
strength was adjusted experimentally to 2.0 to 3.0 T m −1 to maximize the accuracy of fitting from …