mRNA display: ligand discovery, interaction analysis and beyond
TT Takahashi, RJ Austin, RW Roberts - Trends in biochemical sciences, 2003 - cell.com
In vitro peptide and protein selection using mRNA display enables the discovery and directed
evolution of new molecules from combinatorial libraries. These selected molecules can …
evolution of new molecules from combinatorial libraries. These selected molecules can …
Global air-sea flux of CO2: An estimate based on measurements of sea–air pCO2 difference
…, SC Sutherland, TT Takahashi - Proceedings of the …, 1997 - National Acad Sciences
Approximately 250,000 measurements made for the pCO 2 difference between surface
water and the marine atmosphere, ΔpCO 2 , have been assembled for the global oceans. …
water and the marine atmosphere, ΔpCO 2 , have been assembled for the global oceans. …
Directing evolution of novel ligands by mRNA display
G Kamalinia, BJ Grindel, TT Takahashi… - Chemical Society …, 2021 - pubs.rsc.org
mRNA display is a powerful biological display platform for the directed evolution of proteins
and peptides. mRNA display libraries covalently link the displayed peptide or protein (…
and peptides. mRNA display libraries covalently link the displayed peptide or protein (…
[HTML][HTML] Medication overuse and drug addiction: a narrative review from addiction perspective
TT Takahashi, R Ornello, G Quatrosi, A Torrente… - The journal of headache …, 2021 - Springer
Chronic headache is particularly prevalent in migraineurs and it can progress to a condition
known as medication overuse headache (MOH). MOH is a secondary headache caused by …
known as medication overuse headache (MOH). MOH is a secondary headache caused by …
The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators
The conjugation of arginine to proteins is a part of the N-end rule pathway of protein
degradation. Three amino (N)-terminal residues—aspartate, glutamate and cysteine—are …
degradation. Three amino (N)-terminal residues—aspartate, glutamate and cysteine—are …
Detailed analysis of the three-quark potential in SU (3) lattice QCD
TT Takahashi, H Suganuma, Y Nemoto, H Matsufuru - Physical Review D, 2002 - APS
The static three-quark (3Q) potential is studied in detail using SU (3) lattice QCD with 12 3×
24 at β= 5.7 and 16 3× 32 at β= 5.8, 6.0 at the quenched level. For more than 300 different …
24 at β= 5.7 and 16 3× 32 at β= 5.8, 6.0 at the quenched level. For more than 300 different …
[PDF][PDF] Recombinant probes for visualizing endogenous synaptic proteins in living neurons
…, RJ Mora, HB Kwon, CA Olson, TT Takahashi… - Neuron, 2013 - cell.com
The ability to visualize endogenous proteins in living neurons provides a powerful means to
interrogate neuronal structure and function. Here we generate recombinant antibody-like …
interrogate neuronal structure and function. Here we generate recombinant antibody-like …
Three-quark potential in SU (3) lattice QCD
TT Takahashi, H Matsufuru, Y Nemoto, H Suganuma - Physical Review Letters, 2001 - APS
The static three-quark (3 Q) potential is studied in SU (3) lattice QCD with 12 3× 24 and β=
5.7 at the quenched level. From the 3 Q Wilson loop, 3 Q ground-state potential V 3 Q is …
5.7 at the quenched level. From the 3 Q Wilson loop, 3 Q ground-state potential V 3 Q is …
A general route for post-translational cyclization of mRNA display libraries
SW Millward, TT Takahashi… - Journal of the American …, 2005 - ACS Publications
Cyclic peptides are attractive scaffolds for the design of conformationally constrained molecular
therapeutics. Previously, biological display libraries could only be cyclized via disulfide …
therapeutics. Previously, biological display libraries could only be cyclized via disulfide …
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
A major role for the intracellular post-translational modification O-GlcNAc appears to be the
inhibition of protein aggregation. Most of the previous studies in this area focused on O-…
inhibition of protein aggregation. Most of the previous studies in this area focused on O-…