Blood and brain ethanol concentrations during absorption and distribution in long-sleep and short-sleep mice

TN Smolen, A Smolen - Alcohol, 1989 - Elsevier
Smolen, A.; Smolen, TN Demonstration of a threshold concentration for ethanol at the time
of regaining the righting response in long-sleep and short-steep mice. Alcohol Drng Res. 7:…

Identification of genetically homozygous rapid and slow acetylators of drugs and environmental carcinogens among established inbred rabbit strains.

DW Hein, TN Smolen, RR Fox, WW Weber - Journal of Pharmacology and …, 1982 - ASPET
Liver and gut mucosa N-acetyltransferase (NAT) cytosol (105,000 xg) was prepared from
selected lines of New Zealand White rapid and slow acetylator rabbits bred and housed at the …

Alterations in regional brain GABA concentration and turnover during pregnancy

A Smolen, TN Smolen, PC Han - Pharmacology Biochemistry and Behavior, 1993 - Elsevier
… Seyfried, TN; Glaser, GH A review of mouse mutants as genetic models of epilepsy. Epilepsia
26:143-… Smolen, A.; Smolen, TN; Collins, AC Seizure susceptibility of the pregnant mouse. …

Genetic variation in paraoxonase activity and sensitivity to diisopropylphosphofluoridate in inbred mice

…, C Murphy-Erdosh, A Smolen, TN Smolen - Pharmacology …, 1987 - Elsevier
The mechanism underlying genetic variation in the acute and chronic responses of mice to
diisopropylphosphofluoridate (DFP) are unknown. We investigated whether variation in …

Genetically determined differences in acute responses to diisopropylfluorophosphate

A Smolen, TN Smolen, JM Wehner… - … Biochemistry and Behavior, 1985 - Elsevier
The acute effects of diisopropylfluorophosphate (DFP) were assessed in DBA/2Ibg, C57BL/6Ibg
and C3H/2Ibg mice. The DFP was administered by intraperitoneal injection in saline. …

Developmental profile of hepatic alcohol and aldehyde dehydrogenase activities in long-sleep and short-sleep mice

TN Smolen, A Smolen, JL van de Kamp - Alcohol, 1990 - Elsevier
Ethanol is metabolized primarily in the liver by a cytosolic alcohol dehydrogenase (ADH).
The product, acetaldehyde, is metabolized to acetate by nonspecific aldehyde …

Seizure susceptibility of the pregnant mouse

A Smolen, TN Smolen, AC Collins - Pharmacology Biochemistry and …, 1982 - Elsevier
SMOLEN, A., TN SMOLEN AND AC COLLINS. Seizure susceptibility of the pregnant mouse.
PHARMAC. … SMOLEN, SMOLEN AND COLLINS 92 … SMOLEN, SMOLEN AND COLLINS …

Testosterone modulation of N-acetylation in mouse kidney.

TN Smolen, JA Brewer, WW Weber - Journal of Pharmacology and …, 1993 - ASPET
N-acetylation participates in the biotransformation of hydrazine drugs and arylamine carcinogens
to cytotoxic and carcinogenic products. Differences in acetylation capacity expressed …

Strain, sex and developmental profiles of cocaine metabolizing enzymes in mice

D Leibman, A Smolen, TN Smolen - Pharmacology Biochemistry and …, 1990 - Elsevier
SMOLEN AND TN SMOLEN. Strain, sex and developmental profiles of cocaine metabolizing
Smolen, TN; Smolen, A. Developmental expression of cocaine hepatotoxicity in the mouse. …

Sensitivity of inbred and selectively bred mice to ethanol

A Smolen, TN Smolen, JL Van de Kamp - Alcohol, 1987 - Elsevier
Smolen, A., M. Marks, TN Smolen and AC Collins. Dose and route of administration alter the
relative elimination of ethanol by long-sleep and short-sleep mice. Alcoholism: Clin Exp Res …