… [Tm]) to regulate actomyosin binding by making the thin filament less sensitive to Ca2+.…
calcium- and myosin-dependent motions of Tn84 and Tm,37 are opening a whole new area of …

… RE GODT AND TM NOSEK altered by fatigue/hypoxia adequately predicted the observed
changes in F... and Ca2+ sensitivity in both cardiac and skeletal muscle fibres with but one …

The increases in the intracellular concentrations of inorganic phosphate and hydrogen ion
accompanying fatigue of skeletal muscle appear to be the most important metabolic changes …

… TM ( I997). Muscle fatigue and imluetion of stress protein genes: Atlual fultetitm nlteaetive …
and Nosek, TM (I989). Changes of intracellular milieu with fatigue or hypoxia depress …

The ability of skeletal muscle to enhance lipid utilization during exercise is a form of metabolic
plasticity essential for survival. Conversely, metabolic inflexibility in muscle can cause …

The intracellular Ca 2+ concentration ([Ca 2+ ] i ) in skeletal muscles must be rapidly
regulated during the excitation-contraction-relaxation process 1 . However, the signalling …

Reactive oxygen species contribute to diaphragm dysfunction in certain pathophysiological
conditions (ie, sepsis and fatigue). However, the precise alterations induced by reactive …

Experiments from other laboratories suggest that inositol trisphosphate (InsP3) may be involved
in the excitation-contraction coupling (ECC) process of cardiac and skeletal muscle. Our …

Reactive oxygen species such as superoxide (O2-) and H2O2 are produced at low levels in
resting muscles and at substantially higher levels in exercising muscles. Increased …

A lethal form of nemaline myopathy, named "Amish Nemaline Myopathy" (ANM), is linked to
a nonsense mutation at codon Glu 180 in the slow skeletal muscle troponin T (TnT) gene. …