Interactive role of infection, inflammation and traditional risk factors in atherosclerosis and coronary artery disease

JL Mehta, TGP Saldeen, K Rand - Journal of the American College of …, 1998 - jacc.org
… The lipid core of the atherosclerotic region is characterized by the presence of T lymphocytes,
a hallmark of the immune process. The activated T lymphocytes inhibit collagen synthesis …

Tocopherols in the prevention and treatment of atherosclerosis and related cardiovascular disease

P Mathur, Z Ding, T Saldeen, JL Mehta - Clinical cardiology, 2015 - Wiley Online Library
Saldeen et al58 in 1999 observed that although both α-tocopherol and γ-tocopherol
decreased platelet aggregation and delayed thrombus formation, γ-tocopherol was significantly …

Vitamin E and its anticancer effects

A Abraham, AJ Kattoor, T Saldeen… - Critical reviews in food …, 2019 - Taylor & Francis
Vitamin E is a lipid soluble vitamin comprising of eight natural isoforms, namely, α, β, δ, γ
isoforms of tocopherol and α, β, δ, γ isoforms of tocotrienol. Many studies have been performed …

Neutrophil function in ischemic heart disease.

J Mehta, J Dinerman, P Mehta, TG Saldeen… - Circulation, 1989 - Am Heart Assoc
… Wallin R, Saldeen T: A specific radioimmunoassay for determination of peptides derived
from … Saldeen T, Wallin R: A specific radioimmunoassay for peptides derived from human …

Differential effects of α-and γ-tocopherol on low-density lipoprotein oxidation, superoxide activity, platelet aggregation and arterial thrombogenesis

T Saldeen, D Li, JL Mehta - Journal of the American College of Cardiology, 1999 - jacc.org
OBJECTIVES This study was designed to examine the differential effects of α- and γ-tocopherol
on parameters of oxidation-antioxidation and thrombogenesis. BACKGROUND …

The effects of fish oil on triglycerides, cholesterol, fibrinogen and malondialdehyde in humans supplemented with vitamin E

…, R Luostarinen, R Wallin, L Wibell, T Saldeen - The Journal of …, 1991 - Elsevier
… Student's t test for paired observations was used to compare values in the same subjects …
Saldeen, T. (1990) Effects of a new fluid fish oil concentrate, Eskimo-3, on tri glycĂ©rides,…

Statins modulate oxidized low-density lipoprotein-mediated adhesion molecule expression in human coronary artery endothelial cells: role of LOX-1

D Li, H Chen, F Romeo, T Sawamura, T Saldeen… - … of Pharmacology and …, 2002 - ASPET
LOX-1, a receptor for oxidized low-density lipoprotein (ox-LDL), plays a critical role in
endothelial dysfunction and atherosclerosis. LOX-1 activation also plays an important role in …

Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-κB

D Li, T Saldeen, F Romeo, JL Mehta - Circulation, 2000 - Am Heart Assoc
Background—We demonstrated earlier that angiotensin II (Ang II), by AT 1 receptor activation,
upregulates oxidized LDL (ox-LDL) endothelial receptor LOX-1 gene expression and …

Mitochondrial DNA sequencing of shed hairs and saliva on robbery caps: sensitivity and matching probabilities

…, S Meyers, O Handt, T Saldeen… - Journal of …, 1998 - asmedigitalcollection.asme.org
Sequencing of mitochondrial DNA (mtDNA) has been used for human identification based
on teeth and skeletal remains. Here, we describe an amplification system for the mtDNA …

EPA and DHA attenuate ox-LDL-induced expression of adhesion molecules in human coronary artery endothelial cells via protein kinase B pathway

H Chen, D Li, J Chen, GJ Roberts, T Saldeen… - Journal of Molecular and …, 2003 - Elsevier
Uptake of oxidized low-density lipoprotein (ox-LDL) by endothelial cells is a critical step for
the initiation and development of atherosclerosis. Adhesion molecules are inflammatory …