Protective innate immune variants in racial/ethnic disparities of breast and prostate cancer

ST Yeyeodu, LCR Kidd, KS Kimbro - Cancer immunology research, 2019 - AACR
Individuals of African descent are disproportionately affected by specific complex diseases,
such as breast and prostate cancer, which are driven by both biological and nonbiological …

[HTML][HTML] A rapid, inexpensive high throughput screen method for neurite outgrowth

ST Yeyeodu, SM Witherspoon, N Gilyazova… - Current chemical …, 2010 - ncbi.nlm.nih.gov
Neurite outgrowth assays are the most common phenotypic screen to assess chemical
effects on neuronal cells. Current automated assays involve expensive equipment, lengthy …

Contribution of toll-like receptor signaling pathways to breast tumorigenesis and treatment

LCR Kidd, EN Rogers, ST Yeyeodu… - … Cancer: Targets and …, 2013 - Taylor & Francis
Mounting evidence indicates that anomalies in the inflammatory and immune response
pathways are essential to tumorigenesis. However, tumor-based innate immunity initiated by …

In Situ Drug Delivery to Breast Cancer-Associated Extracellular Matrix

JM Fleming, ST Yeyeodu, A McLaughlin… - ACS Chemical …, 2018 - ACS Publications
The extracellular matrix (ECM) contributes to tumor progression through changes induced
by tumor and stromal cell signals that promote increased ECM density and stiffness. The …

[HTML][HTML] IRAK4 and TLR3 Sequence Variants may Alter Breast Cancer Risk among African-American Women

ST Yeyeodu, LCR Kidd, GM Oprea-Ilies… - Frontiers in …, 2013 - frontiersin.org
Mounting evidence suggests that imbalances in immune regulation contribute to cell
transformation. Women of African descent are an understudied group at high risk for developing …

Silver nanoparticles alter epithelial basement membrane integrity, cell adhesion molecule expression, and TGF-β1 secretion

…, JR Enders, LM Costantini, ST Yeyeodu… - … , Biology and Medicine, 2019 - Elsevier
Silver nanoparticles (AgNPs) are widely used in consumer and pharmaceutical products due
to their antipathogenic properties. However, safety concerns have been raised due to their …

Pregnane X Receptor–Humanized Mice Recapitulate Gender Differences in Ethanol Metabolism but Not Hepatotoxicity

K Spruiell, AA Gyamfi, ST Yeyeodu… - … of Pharmacology and …, 2015 - ASPET
Both human and rodent females are more susceptible to developing alcoholic liver disease
following chronic ethanol (EtOH) ingestion. However, little is known about the relative effects …

High‐fat diet induced obesity promotes inflammation, oxidative stress, and hepatotoxicity in female FVB/N mice

…, E Twum, DO Nnamani, ST Yeyeodu… - …, 2024 - Wiley Online Library
Although obesity and subsequent liver injury are increasingly prevalent in women, female
mouse models have generally shown resistance to high‐fat diet (HFD)‐induced obesity. We …

[HTML][HTML] Population-enriched innate immune variants may identify candidate gene targets at the intersection of cancer and cardio-metabolic disease

S Yeyeodu, D Hanafi, K Webb, NA Laurie… - Frontiers in …, 2024 - frontiersin.org
Both cancer and cardio-metabolic disease disparities exist among specific populations in
the US. For example, African Americans experience the highest rates of breast and prostate …

[HTML][HTML] Experimental data demonstrating the effects of silver nanoparticles on basement membrane gene and protein expression in cultured colon, mammary and …

ST Yeyeodu, ME Martin, DK Reaves, JR Enders… - Data in brief, 2019 - Elsevier
This data article is related to the research article entitled “Silver nanoparticles alter epithelial
basement membrane integrity, cell adhesion molecule expression and TGF-beta secretion”, …