MF63 [2-(6-chloro-1H-phenanthro [9, 10-d] imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in …

D Xu, SE Rowland, P Clark, A Giroux, B Côté… - … of Pharmacology and …, 2008 - ASPET
Microsomal prostaglandin E synthase-1 (mPGES-1) is a terminal prostaglandin E 2 (PGE 2 )
synthase in the cyclooxygenase pathway. Inhibitors of mPGES-1 may block PGE 2 …

… -{[4-(5, 9-Diethoxy-6-oxo-6, 8-dihydro-7H-pyrrolo [3, 4-g] quinolin-7-yl)-3-methylbenzyl] sulfonyl}-2-(2-methoxyphenyl) acetamide], a selective E prostanoid receptor 4 …

P Clark, SE Rowland, D Denis, MC Mathieu… - … of Pharmacology and …, 2008 - ASPET
Previous evidence has implicated E prostanoid receptor 4 (EP4) in mechanical hyperalgesia
induced by subplantar inflammation. However, its role in chronic arthritis remains to be …

Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic,[3-(3, 4-difluorophenyl)-4-(4-(methylsulfonyl) phenyl)-2-(5H)-furanone], in multiple …

SE Rowland, P Clark, R Gordon, AK Mullen… - European journal of …, 2007 - Elsevier
Selective type 2 cyclooxygenase (COX-2) inhibitors are often used in preclinical studies
without potency and selectivity data in the experimental species. To address this issue, we …

PALLIATIVE VS DIRECT ACTION STRESS‐REDUCTION PROCEDURES AS TREATMENTS FOR READING DISABILITY

CF Sharpley, SE Rowland - British Journal of Educational …, 1986 - Wiley Online Library
Several previous reports of the treatment of learning disabilities via EMG biofeedback and
relaxation training have suggested that these can be effective in reducing the high levels of …

[HTML][HTML] Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure

…, N Fani, S Carter, LD Sanchez, GE Rowland… - Molecular …, 2023 - nature.com
Considerable racial/ethnic disparities persist in exposure to life stressors and socioeconomic
resources that can directly affect threat neurocircuitry, particularly the amygdala, that …

[HTML][HTML] Prior sexual trauma exposure impacts posttraumatic dysfunction and neural circuitry following a recent traumatic event in the AURORA Study

GE Rowland, A Roeckner, TD Ely, LAM Lebois… - … psychiatry global open …, 2023 - Elsevier
Background Prior sexual trauma (ST) is associated with greater risk for posttraumatic stress
disorder after a subsequent traumatic event; however, the underlying neurobiological …

Neighborhood Disadvantage and Neural Correlates of Threat and Reward Processing in Survivors of Recent Trauma

EK Webb, TD Ely, GE Rowland, LAM Lebois… - JAMA Network …, 2023 - jamanetwork.com
Importance Differences in neighborhood socioeconomic characteristics are important
considerations in understanding differences in risk vs resilience in mental health. Neighborhood …

[PDF][PDF] MF498, a selective EP4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis

P Clark, SE Rowland, D Denis, MC Mathieu… - … of Pharmacology and …, 2008 - Citeseer
Previous evidence has implicated EP4 in mechanical hyperalgesia induced by subplantar
inflammation. However, its role in chronic arthritis remains to be further defined because …

2016 Mitochondria and Chloroplasts Gordon Research Conference and Gordon Research Seminar

K Van Wijk, E Rowland - 2016 - apps.dtic.mil
The 2016 Gordon Research Conference on Mitochondria and Chloroplasts assembled an
international group of scientists investigating theevolution, biogenesis and quality control of …

Sudden arrhythmic death syndrome: familial evaluation identifies inheritable heart disease in the majority of families

…, S Hughes, MT Tome Esteban, E Rowland… - European heart …, 2008 - academic.oup.com
Aims At least 4% of sudden deaths are unexplained at autopsy [sudden arrhythmic death
syndrome (SADS)] and a quarter may be due to inherited cardiac disease. We hypothesized …