User profiles for Stefanie Dedeurwaerdere
Stefanie DedeurwaerdereUCB Pharma Verified email at ucb.com Cited by 2897 |
Neuronuclear assessment of patients with epilepsy
Epilepsy is a common chronic neurological disorder that is controlled with medication in
approximately 70% of cases. When partial seizures are recurrent despite the use of antiepileptic …
approximately 70% of cases. When partial seizures are recurrent despite the use of antiepileptic …
Finding a better drug for epilepsy: antiinflammatory targets
This monograph summarizes one of the sessions of the XI Workshop on Neurobiology of
Epilepsy (WONOEP), and provides a critical review of the current state of the field. Speakers …
Epilepsy (WONOEP), and provides a critical review of the current state of the field. Speakers …
Imaging brain inflammation in epilepsy
H Amhaoul, S Staelens, S Dedeurwaerdere - Neuroscience, 2014 - Elsevier
… The second and last author, Steven Staelens and Stefanie Dedeurwaerdere respectively, …
Halima Amhaoul and Stefanie Dedeurwaerdere are supported by the …
Halima Amhaoul and Stefanie Dedeurwaerdere are supported by the …
Hypolocomotive behaviour associated with increased microglia in a prenatal immune activation model with relevance to schizophrenia
…, S Kumar-Singh, S Dedeurwaerdere - Behavioural brain …, 2014 - Elsevier
Over the past decade a neurodevelopmental animal model with high validity for schizophrenia
has been developed based on the environmental risk factor known as maternal immune …
has been developed based on the environmental risk factor known as maternal immune …
Vagus nerve stimulation for refractory epilepsy: a transatlantic experience
…, V Thadani, K Gilbert, S Dedeurwaerdere… - Journal of Clinical …, 2004 - journals.lww.com
Vagus nerve stimulation (VNS) is an alternative treatment for medically or surgically refractory
epilepsy. The long-term efficacy and safety of VNS were evaluated in a large patient series …
epilepsy. The long-term efficacy and safety of VNS were evaluated in a large patient series …
[HTML][HTML] Thalamic and limbic involvement in the mechanism of action of vagus nerve stimulation, a SPECT study
K Vonck, V De Herdt, T Bosman, S Dedeurwaerdere… - Seizure, 2008 - Elsevier
PURPOSE: To unravel the mechanism of action of neurostimulation as a treatment for
seizures, functional neuroimaging tools allow minimally invasive research in humans. We …
seizures, functional neuroimaging tools allow minimally invasive research in humans. We …
[HTML][HTML] PET imaging of brain inflammation during early epileptogenesis in a rat model of temporal lobe epilepsy
S Dedeurwaerdere, PD Callaghan, T Pham… - EJNMMI research, 2012 - Springer
Background Recently, inflammatory cascades have been suggested as a target for epilepsy
therapy. Positron emission tomography (PET) imaging offers the unique possibility to …
therapy. Positron emission tomography (PET) imaging offers the unique possibility to …
[HTML][HTML] Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy
Neuronal dysfunction due to iron accumulation in conjunction with reactive oxygen species (ROS)
could represent an important, yet underappreciated, component of the epileptogenic …
could represent an important, yet underappreciated, component of the epileptogenic …
Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis
…, S Staelens, S Dedeurwaerdere - Neurobiology of …, 2015 - Elsevier
Aims A hallmark in the neuropathology of temporal lobe epilepsy is brain inflammation which
has been suggested as both a biomarker and a new mechanistic target for treatments. The …
has been suggested as both a biomarker and a new mechanistic target for treatments. The …
[HTML][HTML] Kainic acid-induced post-status epilepticus models of temporal lobe epilepsy with diverging seizure phenotype and neuropathology
…, S Van De Vijver, I Ali, S Dedeurwaerdere - Frontiers in …, 2017 - frontiersin.org
The aim of epilepsy models is to investigate disease ontogenesis and therapeutic interventions
in a consistent and prospective manner. The kainic acid-induced status epilepticus (…
in a consistent and prospective manner. The kainic acid-induced status epilepticus (…