Epilepsy is a common chronic neurological disorder that is controlled with medication in
approximately 70% of cases. When partial seizures are recurrent despite the use of antiepileptic …

This monograph summarizes one of the sessions of the XI Workshop on Neurobiology of
Epilepsy (WONOEP), and provides a critical review of the current state of the field. Speakers …

… The second and last author, Steven Staelens and Stefanie Dedeurwaerdere respectively, …
Halima Amhaoul and Stefanie Dedeurwaerdere are supported by the …

Over the past decade a neurodevelopmental animal model with high validity for schizophrenia
has been developed based on the environmental risk factor known as maternal immune …

Vagus nerve stimulation (VNS) is an alternative treatment for medically or surgically refractory
epilepsy. The long-term efficacy and safety of VNS were evaluated in a large patient series …

PURPOSE: To unravel the mechanism of action of neurostimulation as a treatment for
seizures, functional neuroimaging tools allow minimally invasive research in humans. We …

Background Recently, inflammatory cascades have been suggested as a target for epilepsy
therapy. Positron emission tomography (PET) imaging offers the unique possibility to …

Neuronal dysfunction due to iron accumulation in conjunction with reactive oxygen species (ROS)
could represent an important, yet underappreciated, component of the epileptogenic …

Aims A hallmark in the neuropathology of temporal lobe epilepsy is brain inflammation which
has been suggested as both a biomarker and a new mechanistic target for treatments. The …

The aim of epilepsy models is to investigate disease ontogenesis and therapeutic interventions
in a consistent and prospective manner. The kainic acid-induced status epilepticus (…