Core fucosylation of E‐cadherin enhances cell–cell adhesion in human colon carcinoma WiDr cells
D Osumi, M Takahashi, E Miyoshi, S Yokoe… - Cancer …, 2009 - Wiley Online Library
α1,6‐Fucosyltransferase (Fut8), an enzyme that catalyzes the introduction of α1,6 core fucose
to the innermost N‐acetylglucosamine residue of the N‐glycan, has been implicated in the …
to the innermost N‐acetylglucosamine residue of the N‐glycan, has been implicated in the …
Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy
S Yokoe, M Asahi, T Takeda, K Otsu, N Taniguchi… - …, 2010 - academic.oup.com
Cardiac-type sarco(endo)plasmic reticulum Ca 2 -ATPase (SERCA2a) plays a major role in
cardiac muscle contractility. Phospholamban (PLN) regulates the function of SERCA2a via …
cardiac muscle contractility. Phospholamban (PLN) regulates the function of SERCA2a via …
Metformin increases degradation of phospholamban via autophagy in cardiomyocytes
ACT Teng, T Miyake, S Yokoe… - Proceedings of the …, 2015 - National Acad Sciences
Phospholamban (PLN) is an effective inhibitor of the sarco(endo)plasmic reticulum Ca 2+
ATPase (SERCA). Here, we examined PLN stability and degradation in primary cultured …
ATPase (SERCA). Here, we examined PLN stability and degradation in primary cultured …
N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion
M Takahashi, S Yokoe, M Asahi, SH Lee, W Li… - … et Biophysica Acta (BBA …, 2008 - Elsevier
More and more evidence indicates that N-glycan regulates signal transduction by modulating
receptor functions. Previous studies suggested that glycosylation of EGFR is involved in …
receptor functions. Previous studies suggested that glycosylation of EGFR is involved in …
The Asn418-Linked N-Glycan of ErbB3 Plays a Crucial Role in Preventing Spontaneous Heterodimerization and Tumor Promotion
S Yokoe, M Takahashi, M Asahi, SH Lee, W Li… - Cancer research, 2007 - AACR
ErbB2 and ErbB3, two members of the ErbB family, form a high-affinity heregulin coreceptor
that elicits potent mitogenic and transforming signals, and clinical studies indicate that these …
that elicits potent mitogenic and transforming signals, and clinical studies indicate that these …
Interleukin-18 gene deletion protects against sepsis-induced cardiac dysfunction by inhibiting PP2A activity
Y Okuhara, S Yokoe, T Iwasaku, A Eguchi… - International Journal of …, 2017 - Elsevier
Background Interleukin-18 (IL-18) neutralization protects against lipopolysaccharide (LPS)-induced
injuries, including myocardial dysfunction. However, the mechanism is yet to be fully …
injuries, including myocardial dysfunction. However, the mechanism is yet to be fully …
Augmented O-GlcNAcylation exacerbates right ventricular dysfunction and remodeling via enhancement of hypertrophy, mitophagy, and fibrosis in mice exposed to …
S Yokoe, T Hayashi, T Nakagawa, R Kato, Y Ijiri… - Hypertension …, 2023 - nature.com
Previously, we showed that augmented O-linked N-acetylglucosaminylation (O-GlcNAcylation)
mitigates cardiac remodeling in O-GlcNAc transferase-transgenic (Ogt-Tg) mice exposed …
mitigates cardiac remodeling in O-GlcNAc transferase-transgenic (Ogt-Tg) mice exposed …
Autophagy deficiency diminishes indomethacin-induced intestinal epithelial cell damage through activation of the ERK/Nrf2/HO-1 pathway
S Harada, T Nakagawa, S Yokoe, S Edogawa… - … of Pharmacology and …, 2015 - ASPET
Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause epithelial cell damage in the
stomach, intestine, and colon. NSAIDs are reported to induce autophagy and apoptosis in …
stomach, intestine, and colon. NSAIDs are reported to induce autophagy and apoptosis in …
[HTML][HTML] Fluctuation in O-GlcNAcylation inactivates STIM1 to reduce store-operated calcium ion entry via down-regulation of Ser621 phosphorylation
A Nomura, S Yokoe, K Tomoda, T Nakagawa… - Journal of Biological …, 2020 - ASBMB
Stromal interaction molecule 1 (STIM1) plays a pivotal role in store-operated Ca 2+ entry (SOCE),
an essential mechanism in cellular calcium signaling and in maintaining cellular …
an essential mechanism in cellular calcium signaling and in maintaining cellular …
Acrolein produces nitric oxide through the elevation of intracellular calcium levels to induce apoptosis in human umbilical vein endothelial cells: implications for smoke …
Y Misonou, M Asahi, S Yokoe, E Miyoshi, N Taniguchi - Nitric Oxide, 2006 - Elsevier
Acrolein is a highly electrophilic α, β-unsaturated aldehyde, the levels of which are increased
in the blood of smokers. To determine if acrolein is involved in the pathology of smoke …
in the blood of smokers. To determine if acrolein is involved in the pathology of smoke …