[HTML][HTML] The postoperative bleeding rate and its risk factors in patients on antithrombotic therapy who undergo gastric endoscopic submucosal dissection

T Takeuchi, K Ota, S Harada, S Edogawa, Y Kojima… - BMC …, 2013 - Springer
Background There is a lack of consensus regarding the risk of postoperative hemorrhage in
patients on antithrombotic therapy who undergo endoscopic submucosal dissection (ESD). …

Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS

S Edogawa, AL Edwinson, SA Peters… - Gut, 2020 - gut.bmj.com
Objective The intestinal lumen contains several proteases. Our aim was to determine the
role of faecal proteases in mediating barrier dysfunction and symptoms in IBS. Design 39 …

[HTML][HTML] Sex differences in NSAID-induced perturbation of human intestinal barrier function and microbiota

S Edogawa, SA Peters, GD Jenkins… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Intestinal barrier function and microbiota are integrally related and play critical roles in
maintenance of host physiology. Sex is a key biologic variable for several disorders. Our aim was …

A novel endoscopic submucosal dissection technique for proton pump inhibitor-refractory gastroesophageal reflux disease

K Ota, T Takeuchi, S Harada, S Edogawa… - Scandinavian Journal …, 2014 - Taylor & Francis
Objectives: Although drug treatment is the usual first-line therapy for gastroesophageal reflux
disease (GERD), not all patients receive satisfactory relief from drug therapy, alone. We …

Constipation-predominant irritable bowel syndrome females have normal colonic barrier and secretory function

SA Peters, S Edogawa, WJ Sundt… - Official journal of the …, 2017 - journals.lww.com
OBJECTIVES: The objective of this study was to determine whether constipation-predominant
irritable bowel syndrome (IBS-C) is associated with changes in intestinal barrier and …

Autophagy deficiency diminishes indomethacin-induced intestinal epithelial cell damage through activation of the ERK/Nrf2/HO-1 pathway

S Harada, T Nakagawa, S Yokoe, S Edogawa… - … of Pharmacology and …, 2015 - ASPET
Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause epithelial cell damage in the
stomach, intestine, and colon. NSAIDs are reported to induce autophagy and apoptosis in …

Potential predictors of disease progression for main‐duct intraductal papillary mucinous neoplasms of the pancreas

…, D Masuda, Y Kurisu, S Edogawa… - Journal of …, 2013 - Wiley Online Library
Background and Aim The evidence for main pancreatic duct intraductal papillary mucinous
neoplasms ( MPD ‐ IPMN ) malignancy is based predominantly on investigation of resected …

Current topics of strategy of NSAID-induced small intestinal lesions

S Edogawa, T Takeuchi, Y Kojima, K Ota, S Harada… - Digestion, 2015 - karger.com
Small intestinal mucosal injuries have been recently recognized as common complications
associated with non-steroidal anti-inflammatory drugs (NSAIDs) because video capsule …

Determination of the adequate dosage of rebamipide, a gastric mucoprotective drug, to prevent low-dose aspirin-induced gastrointestinal mucosal injury

…, Y Takahashi, S Harada, S Edogawa… - Journal of Clinical …, 2016 - jstage.jst.go.jp
Small intestinal mucosal injury caused by low-dose aspirin is a common cause of obscure
gastrointestinal bleeding. We aimed to investigate the protective effects and optimal dose of …

Liver abscess caused by CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Salmonella enteritidis

A Imoto, Y Ooi, S Edogawa, T Ogura, D Masuda… - Internal …, 2014 - jstage.jst.go.jp
Liver abscesses secondary to Salmonella species are rarely described in the general
population. We herein describe a case of a liver abscess caused by CTX-M-55-type extended-…