Control of regional blood flow by endothelium-derived nitric oxide.

SM Gardiner, AM Compton, T Bennett, RM Palmer… - …, 1990 - Am Heart Assoc
The regional hemodynamic consequences of inhibiting vascular endothelial nitric oxide
generation with NG-monomethyl-L-arginine (L-NMMA) were studied in conscious Long-Evans …

A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle

…, D Constantin‐Teodosiu, SM Gardiner… - The Journal of …, 2008 - Wiley Online Library
Sepsis causes muscle atrophy and insulin resistance, but the underlying mechanisms are
unclear. Therefore, the present study examined the effects of lipopolysaccharide (LPS)‐…

Characterization of the endokinins: human tachykinins with cardiovascular activity

NM Page, NJ Bell, SM Gardiner… - Proceedings of the …, 2003 - National Acad Sciences
We report four human tachykinins, endokinins A, B, C, and D (EKA–D), encoded from a single
tachykinin precursor 4 gene that generates four mRNAs (α, β, γ, and δ). Tachykinin 4 gene …

An endogenous cannabinoid as an endothelium-derived vasorelaxant

…, T Bennett, EA Boyd, JR Fry, SM Gardiner… - Biochemical and …, 1996 - Elsevier
Since the identification of nitric oxide (NO) as an important mediator of endothelium-dependent
relaxation, it has become clear that there is an additional endothelial relaxant factor, …

Nitric oxide synthase inhibitors cause sustained, but reversible, hypertension and hindquarters vasoconstriction in Brattleboro rats

SM Gardiner, PA Kemp, T Bennett, RMJ Palmer… - European journal of …, 1992 - Elsevier
Homozygous male Brattleboro rats were given a solution of N G -monomethyl-L-arginine (L-NMMA;
1 mg ml −1 ) to drink for a period of 7 days. There was a persistent elevation of mean …

Low‐dose dexamethasone prevents endotoxaemia‐induced muscle protein loss and impairment of carbohydrate oxidation in rat skeletal muscle

…, PL Greenhaff, SM Gardiner - The Journal of …, 2010 - Wiley Online Library
We recently provided evidence suggesting a role for cytokine‐mediated inhibition of Akt/Forkhead
box O 1 (FOXO1) signalling in the induction of muscle atrophy and impairment of …

Regional haemodynamic changes during oral ingestion of NG‐monomethyl‐l‐arginine or NG‐nitro‐l‐arginine methyl ester in conscious Brattleboro rats

SM Gardiner, AM Compton, T Bennett… - British journal of …, 1990 - Wiley Online Library
Homozygous Brattleboro (ie vasopressin‐deficient) rats were chronically instrumented with
pulsed Doppler probes and intravascular catheters to permit continuous monitoring of …

Maternal fructose and/or salt intake and reproductive outcome in the rat: effects on growth, fertility, sex ratio, and birth order

C Gray, S Long, C Green, SM Gardiner… - Biology of …, 2013 - academic.oup.com
Maternal diet can significantly skew the secondary sex ratio away from the expected value of
0.5 (proportion males), but the details of how diet may do this are unclear. Here, we altered …

Mesenteric vasoconstriction and hindquarters vasodilatation accompany the pressor actions of exendin-4 in conscious rats

SM Gardiner, JE March, PA Kemp, T Bennett - Journal of Pharmacology and …, 2006 - ASPET
The hemodynamic effects of the glucagon-like peptide-1 (GLP-1) receptor agonist, exendin-4,
and putative underlying mechanisms were assessed in conscious male Sprague-Dawley …

Excess maternal salt or fructose intake programmes sex-specific, stress-and fructose-sensitive hypertension in the offspring

C Gray, SM Gardiner, M Elmes… - British Journal of …, 2016 - cambridge.org
The Western diet is typically high in salt and fructose, which have pressor activity. Maternal
diet can affect offspring blood pressure, but the extent to which maternal intake of excess salt …