User profiles for Sean X. Naughton
Sean X NaughtonMount Sinai Verified email at mssm.edu Cited by 922 |
Neurotoxicity in acute and repeated organophosphate exposure
SX Naughton, AV Terry Jr - Toxicology, 2018 - Elsevier
The term organophosphate (OP) refers to a diverse group of chemicals that are found in
hundreds of products worldwide. As pesticides, their most common use, OPs are clearly …
hundreds of products worldwide. As pesticides, their most common use, OPs are clearly …
[HTML][HTML] Potential novel role of COVID-19 in Alzheimer's disease and preventative mitigation strategies
SX Naughton, U Raval… - Journal of Alzheimer's …, 2020 - content.iospress.com
There are a number of potential implications for the field of Alzheimer’s disease (AD) stemming
from the global spread of SARS-CoV-2. Neuroinflammation is known to be a prominent …
from the global spread of SARS-CoV-2. Neuroinflammation is known to be a prominent …
[HTML][HTML] The innate immune system and inflammatory priming: potential mechanistic factors in mood disorders and Gulf War illness
…, M Sebastian-Valverde, SX Naughton… - Frontiers in …, 2020 - frontiersin.org
Gulf War Illness is a chronic multisystem disorder affecting approximately a third of the Veterans
of the Gulf War, manifesting with physical and mental health symptoms such as cognitive …
of the Gulf War, manifesting with physical and mental health symptoms such as cognitive …
Repeated exposure to chlorpyrifos leads to prolonged impairments of axonal transport in the living rodent brain
CM Hernandez, WD Beck, SX Naughton, I Poddar… - Neurotoxicology, 2015 - Elsevier
The toxicity of the class of chemicals known as the organophosphates (OP) is most
commonly attributed to the inhibition of the enzyme acetylcholinesterase. However, there is …
commonly attributed to the inhibition of the enzyme acetylcholinesterase. However, there is …
Chlorpyrifos and chlorpyrifos oxon impair the transport of membrane bound organelles in rat cortical axons
J Gao, SX Naughton, WD Beck, CM Hernandez, G Wu… - Neurotoxicology, 2017 - Elsevier
Chlorpyrifos (CPF) is an extensively used organophosphorus pesticide that has recently
come under increasing scrutiny due to environmental health concerns particularly its …
come under increasing scrutiny due to environmental health concerns particularly its …
[HTML][HTML] The viral hypothesis in Alzheimer's disease: Novel insights and pathogen-based biomarkers
SX Naughton, U Raval, GM Pasinetti - Journal of Personalized Medicine, 2020 - mdpi.com
Early diagnosis of Alzheimer’s disease (AD) and the identification of significant risk factors
are necessary to better understand disease progression, and to develop intervention-based …
are necessary to better understand disease progression, and to develop intervention-based …
Cocaine-induced neuroadaptations in the dorsal striatum: glutamate dynamics and behavioral sensitization
Recent evidence suggests that diminished ability to control cocaine seeking arises from
perturbations in glutamate homeostasis in the nucleus accumbens. However, the neurochemical …
perturbations in glutamate homeostasis in the nucleus accumbens. However, the neurochemical …
Diminished trk A receptor signaling reveals cholinergic‐attentional vulnerability of aging
…, WM Howe, RM Welchko, SX Naughton… - European Journal of …, 2013 - Wiley Online Library
The cellular mechanisms underlying the exceptional vulnerability of the basal forebrain ( BF
) cholinergic neurons during pathological aging have remained elusive. Here we employed …
) cholinergic neurons during pathological aging have remained elusive. Here we employed …
Diisopropylfluorophosphate impairs the transport of membrane-bound organelles in rat cortical axons
J Gao, SX Naughton, H Wulff, V Singh, WD Beck… - … of Pharmacology and …, 2016 - ASPET
The extensive use of organophosphates (OPs) is an ongoing environmental health concern
due to multiple reports of OP-related neurologic abnormalities. The mechanism of the acute …
due to multiple reports of OP-related neurologic abnormalities. The mechanism of the acute …
Repeated exposures to diisopropylfluorophosphate result in structural disruptions of myelinated axons and persistent impairments of axonal transport in the brains of …
SX Naughton, CM Hernandez, WD Beck, I Poddar… - Toxicology, 2018 - Elsevier
Organophosphates (OPs) are found in hundreds of valuable agricultural, industrial, and
commercial compounds; however, they have also been associated with a variety of harmful …
commercial compounds; however, they have also been associated with a variety of harmful …