3D printing of scaffolds for tissue regeneration applications
AV Do, B Khorsand, SM Geary… - Advanced healthcare …, 2015 - Wiley Online Library
The current need for organ and tissue replacement, repair, and regeneration for patients is
continually growing such that supply is not meeting demand primarily due to a paucity of …
continually growing such that supply is not meeting demand primarily due to a paucity of …
Biodegradable particles as vaccine delivery systems: size matters
Poly(lactide-co-glycolide) (PLGA) particles have strong potential as antigen delivery systems.
The size of PLGA particles used to vaccinate mice can affect the magnitude of the antigen-…
The size of PLGA particles used to vaccinate mice can affect the magnitude of the antigen-…
Nanoparticle delivery systems in cancer vaccines
Y Krishnamachari, SM Geary, CD Lemke… - Pharmaceutical …, 2011 - Springer
Therapeutic strategies that involve the manipulation of the host’s immune system are gaining
momentum in cancer research. Antigen-loaded nanocarriers are capable of being actively …
momentum in cancer research. Antigen-loaded nanocarriers are capable of being actively …
Characterization of mice lacking the tetraspanin superfamily member CD151
The tetraspanin membrane protein CD151 is a broadly expressed molecule noted for its
strong molecular associations with integrins, especially α3β1, α6β1, α7β1, and α6β4. In vitro …
strong molecular associations with integrins, especially α3β1, α6β1, α7β1, and α6β4. In vitro …
Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells
…, IA Mudunkotuwa, SM Geary… - Environmental …, 2016 - pubs.rsc.org
The increasing use of copper oxide (CuO) nanoparticles (NPs) in medicine and industry
demands an understanding of their potential toxicities. In this study, we compared the in vitro …
demands an understanding of their potential toxicities. In this study, we compared the in vitro …
Evolution of drug-eluting biomedical implants for sustained drug delivery
JC Quarterman, SM Geary, AK Salem - European journal of pharmaceutics …, 2021 - Elsevier
In the field of drug delivery, the most commonly used treatments have traditionally been
systemically delivered using oral or intravenous administration. The problems associated with …
systemically delivered using oral or intravenous administration. The problems associated with …
Bone regeneration using gene-activated matrices
Gene delivery to bone is a potential therapeutic strategy for directed, sustained, and regulated
protein expression. Tissue engineering strategies for bone regeneration include delivery …
protein expression. Tissue engineering strategies for bone regeneration include delivery …
Nanoparticle-based delivery of CRISPR/Cas9 genome-editing therapeutics
The recent progress in harnessing the efficient and precise method of DNA editing provided
by CRISPR/Cas9 is one of the most promising major advances in the field of gene therapy. …
by CRISPR/Cas9 is one of the most promising major advances in the field of gene therapy. …
Tissue engineering for the temporomandibular joint
Tissue engineering potentially offers new treatments for disorders of the temporomandibular
joint which frequently afflict patients. Damage or disease in this area adversely affects …
joint which frequently afflict patients. Damage or disease in this area adversely affects …
Mitochondria-targeting particles
A Wongrakpanich, SM Geary, MA Joiner… - …, 2014 - Future Medicine
Mitochondria are a promising therapeutic target for the detection, prevention and treatment
of various human diseases such as cancer, neurodegenerative diseases, ischemia-…
of various human diseases such as cancer, neurodegenerative diseases, ischemia-…