Brain-derived neurotrophic factor (BDNF) and serotonin (5-hydroxytryptamine, 5-HT) are
known to regulate synaptic plasticity, neurogenesis and neuronal survival in the adult brain. …

GnRH and its analogs are used extensively for the treatment of hormone-dependent diseases
and assisted reproductive techniques. They also have potential as novel contraceptives in …

The vulnerability of the nervous system to advancing age is all too often manifest in
neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. In this review article we …

The Ras-dependent activation of mitogen-activated protein (MAP) kinase pathways by
many receptors coupled to heterotrimeric guanine nucleotide binding proteins (G proteins) …

… Ash S, Reeves MM, Yeo S, Morrison G, Carey D, Capra S . Effect of intensive dietetic
interventions on weight and glycaemic control in overweight men with Type II diabetes: a …

… The mechanism(s) by which ADCR reduces oxidative stress and inflammation in asthmatic
subjects remains to be established. However, based on previous studies of the effects of …

Intermittent energy restriction may result in greater improvements in insulin sensitivity and
weight control than daily energy restriction (DER). We tested two intermittent energy and …

… Protein kinase A-mediated phosphorylation of the β 2 AR following G s -dependent activation
of adenylate cyclase results in enhanced coupling between the β 2 AR and G i proteins ( …

… ’s, Parkinson’s and Huntington’s diseases, and stroke? The most widely used models of
Alzheimer’s … Such “Alzheimer’s mice” develop progressive accumulation of amyloid β-peptide, …

Huntington's disease is a fatal neurodegenerative disorder caused by an expanded
polyglutamine repeat in huntingtin (HTT) protein. We previously showed that calorie restriction …