A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain

…, M Ohata, S Jenab, AW Sailer, S Malkmus… - Journal of …, 2003 - Soc Neuroscience
… A, Immunolabeling for GFP in the primary sensory neurons of the DRGs produced only a
light background labeling over the somata (S) and no labeling of the dorsal root afferents (DRA)…

An automated flinch detecting system for use in the formalin nociceptive bioassay

…, M Rathbun, C Svensson, S Malkmus… - Journal of applied …, 2001 - journals.physiology.org
… ;2) a window displaying the previous 2 s of digitized signal with markers indicating any flinch
… ) smoothed range waveform signal of previous 2 s with indicators for flinch activity and flinch …

Femtosecond fluorescence and absorption dynamics of an azobenzene with a strong push− pull substitution

…, C Sobotta, S Malkmus, S Laimgruber… - The Journal of …, 2004 - ACS Publications
The ultrafast photoisomerization of a push−pull substituted azobenzene (4-nitro-4‘-(dimethylamino)azobenzene,
NA) is studied by means of femtosecond fluorescence and absorption …

Studies on the safety of chronically administered intrathecal neostigmine methylsulfate in rats and dogs

TL Yaksh, MR Grafe, S Malkmus… - The Journal of the …, 1995 - pubs.asahq.org
… Injections were delivered over 30 s using a hand-driven syringe pump. … If no response
occurred in 60 s, the animal was removed and that time assigned as the response. Data are …

Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death

HS Ilieva, K Yamanaka, S Malkmus… - Proceedings of the …, 2008 - National Acad Sciences
Dominant mutations in cytoplasmic dynein (Loa or Cra) have been reported to provoke selective,
age-dependent killing of motor neurons, while paradoxically slowing degeneration and …

Synthesis and Biological Activities of Cyclic Lanthionine Enkephalin Analogues:  δ-Opioid Receptor Selective Ligands

Y Rew, S Malkmus, C Svensson, TL Yaksh… - Journal of medicinal …, 2002 - ACS Publications
… The combined organic layers were rinsed with saturated aqueous Na 2 S 2 O 3 solution (300
mL), saturated aqueous CuSO 4 solution (… where the cutoff latency was 20 s in this study. …

Comparing a photoinduced pericyclic ring opening and closure: Differences in the excited state pathways

…, S Malkmus, S Laimgruber, S Dietrich… - Journal of the …, 2007 - ACS Publications
… Here, we assume that the measured signal S(λ, τ) can be modeled using a sum of
exponential decays convoluted with a Gaussian instrumental response function IRF: …

Role of Meningeal Mast Cells in Intrathecal Morphine–evoked Granuloma Formation

…, SL Veesart, KA Horais, SA Malkmus… - The Journal of the …, 2013 - pubs.asahq.org
Materials and Methods All studies described in this article were accomplished under method
protocols approved by the Institutional Animal Care and Use Committee of the University of …

Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour

TJS Shi, X Hua, X Lu, S Malkmus… - European Journal of …, 2006 - Wiley Online Library
… at 94 C for 30 s and annealing/extension at 70 C for 50 s and a final extension at 70 C … s,
35 cycles of denaturation at 95 C for 8 s, annealing at 55 C for 10 s, extension at 72 C for 60 s

Intrathecal catheterization and drug delivery in the rat

SA Malkmus, TL Yaksh - Pain Research: Methods and Protocols, 2004 - Springer
… This injection takes approx 15 s. If there is resistance, and the bubble does not move, the
catheter may be clogged. The catheter is always unclogged with saline, not with the drug being …