User profiles for S. Kulasegram

Sivakumar Kulasegaram

Cardiff University
Verified email at cardiff.ac.uk
Cited by 2602

Correction and stabilization of smooth particle hydrodynamics methods with applications in metal forming simulations

J Bonet, S Kulasegaram - International journal for numerical …, 2000 - Wiley Online Library
… Smooth particle hydrodynamics (SPH) is a robust and … For simplicity in this paper the SPH
method with the corrected kernel is … It is also shown that the nodal integration of this corrected …

Structure-guided design of a selective BCL-XL inhibitor

…, P Gibbons, WJA Kersten, S Kulasegaram… - Nature chemical …, 2013 - nature.com
… As the evasion of apoptosis is critical for cancer development and imposes a major barrier …
tumor cells is a compelling therapeutic goal 1 . The major gateway to apoptosis is guarded by …

A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid

…, T Bisogno, W Williams, MC Grier, S Kulasegram… - … of Pharmacology and …, 2002 - ASPET
… CB 1 receptor ligand anandamide and capsaicin, is a potent agonist for the capsaicin receptor
… Although none of these behavioral assays taken alone is indicative of a particular class of …

Generalized shear deformation theory for functionally graded isotropic and sandwich plates based on isogeometric approach

CH Thai, S Kulasegaram, LV Tran… - Computers & Structures, 2014 - Elsevier
A generalized shear deformation theory for static, dynamic and buckling analysis of functionally
graded material (FGM) made of isotropic and sandwich plates is presented in this paper. …

A variational formulation based contact algorithm for rigid boundaries in two-dimensional SPH applications

S Kulasegaram, J Bonet, RW Lewis, M Profit - Computational Mechanics, 2004 - Springer
is the particle position, vh xJ š Ž is the approximated (or interpolated) value of the velocity
at point J and vJ is … was developed by Bonet and Kulasegaram [10] to enforce essential …

[HTML][HTML] Isogeometric analysis of functionally graded plates using a refined plate theory

…, LV Tran, CH Thai, S Kulasegaram… - Composites Part B …, 2014 - Elsevier
… Using RPT models, the axial stress is similar to the other models we compared to while
there is a slight difference observed for shear stress distribution. Note that all models presented …

New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis

…, MG Cascio, G Pryce, S Kulasegram… - British journal of …, 2006 - Wiley Online Library
We previously reported that the compound O‐2093 is a selective inhibitor of the reuptake of
the endocannabinoid anandamide (AEA). We have now re‐examined the activity of O‐2093 …

Variational formulation for the smooth particle hydrodynamics (SPH) simulation of fluid and solid problems

J Bonet, S Kulasegaram, MX Rodriguez-Paz… - Computer Methods in …, 2004 - Elsevier
The paper describes the variational formulation of smooth particle hydrodynamics for both
fluids and solids applications. The resulting equations treat the continuum as a Hamiltonian …

Remarks on tension instability of Eulerian and Lagrangian corrected smooth particle hydrodynamics (CSPH) methods

J Bonet, S Kulasegaram - International Journal for Numerical …, 2001 - Wiley Online Library
… Bonet J, Kulasegaram S. Correction and stabilisation of smooth particle hydrodynamics
methods with applications in metal forming simulations. International Journal for Numerical …

Reorientation of short steel fibres during the flow of self-compacting concrete mix and determination of the fibre orientation factor

R Deeb, BL Karihaloo, S Kulasegaram - Cement and Concrete Research, 2014 - Elsevier
… It is elliptical if z si is not equal to z ei and θ i isis most effective if it is perpendicular to the
cross-section; it is completely ineffective if it lies in the section; a fibre inclined to the section is