Objective The risk-benefit profile of antidepressant medications in bipolar disorder is
controversial. When conclusive evidence is lacking, expert consensus can guide treatment …

Replicated international studies have underscored the human and societal costs associated
with major depressive disorder. Despite the proven efficacy of monoamine-based …

… A central feature of quality of life is an individual’s ability to perform … Paykel22 described
social functioning as “an individual’s ability to function within their usual environment.”(pS9) …

Background Docetaxel-based chemotherapy is effective in metastatic gastric and gastro-oesophageal
junction adenocarcinoma. This study reports on the safety and efficacy of the …

… Patients were randomly assigned in a 2:1 ratio to receive intravenous nivolumab (Opdivo,
Bristol-Myers Squibb) or a standard, single-agent therapy of the investigator’s choice, with …

In this report, which is an update of a guideline published in 2002 (Bandelow et al. 2002,
World J Biol Psychiatry 3:171), recommendations for the pharmacological treatment of anxiety …

… seasonal change was experienced as a problem, Kasper et al. developed criteria based
on the … For purposes of comparison with that study, we computed Pearson’s product-moment …

Background Attention-deficit/hyperactivity disorder (ADHD) is among the most common
psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD is …

Objective: This review aimed to provide distinct dose recommendations for antidepressants
based on the genotypes of cytochrome P450 enzymes CYP2D6 and CYP2C19. This …

Patterns of seasonal changes in mood and behavior in Montgomery County, Maryland, were
evaluated in randomly selected household samples by lay interviewers using a telephone …