User profiles for S. Gaetani

Silvana Gaetani

Sapienza University of Rome
Verified email at uniroma1.it
Cited by 10722

[HTML][HTML] Cannabinoid receptor 2 signaling in neurodegenerative disorders: from pathogenesis to a promising therapeutic target

…, L Pace, F De Marco, A Romano, S Gaetani - Frontiers in …, 2017 - frontiersin.org
As a consequence of an increasingly aging population, the number of people affected by
neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease and …

Regulation of food intake by oleoylethanolamide

J Lo Verme, S Gaetani, J Fu, F Oveisi, K Burton… - Cellular and molecular …, 2005 - Springer
… ANOVA (analysis of variance) followed by Bonferroni’s multiple comparison test (n = 4–5). …
ANOVA followed by a Dunnett’s test. Significantly different from vehicle: *, p < 0.05; …

[HTML][HTML] From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders

…, MV Micioni Di Bonaventura, S Gaetani - Frontiers in …, 2016 - frontiersin.org
Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and
supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a …

Modulation of anxiety through blockade of anandamide hydrolysis

S Kathuria, S Gaetani, D Fegley, F Valiño, A Duranti… - Nature medicine, 2003 - nature.com
… Session duration was 20 min for adult rats and 60 s for 10-day-old pups. We analyzed data
… and lasted for 15 s. Drugs were administered after baseline value collection (15 s) and pups …

An anorexic lipid mediator regulated by feeding

…, A Giuffrida, J LoVerme, S Gaetani, S Kathuria… - Nature, 2001 - nature.com
Oleylethanolamide (OEA) is a natural analogue of the endogenous cannabinoid anandamide.
Like anandamide, OEA is produced in cells in a stimulus-dependent manner and is …

Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α

J Fu, S Gaetani, F Oveisi, J Lo Verme, A Serrano… - Nature, 2003 - nature.com
… We constructed a pGEX-α plasmid containing the gene encoding glutathione S-transferase
(GST) fused to the LBD of human PPAR-α by subcloning the LBD fragment into pGEX-4T (…

Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3′-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and …

D Fegley, S Gaetani, A Duranti, A Tontini, M Mor… - … of Pharmacology and …, 2005 - ASPET
Fatty acid amide hydrolase (FAAH) is an intracellular serine enzyme that catalyzes the
hydrolysis of bioactive fatty acid ethanolamides such as anandamide and oleoylethanolamide (…

Oleoylethanolamide, an endogenous PPAR-α agonist, lowers body weight and hyperlipidemia in obese rats

J Fu, F Oveisi, S Gaetani, E Lin, D Piomelli - Neuropharmacology, 2005 - Elsevier
The fatty-acid ethanolamide, oleoylethanolamide (OEA), is a naturally occurring lipid that
regulates feeding and body weight [Rodríguez de Fonseca, F., Navarro, M., Gómez, R., …

[HTML][HTML] The lipid messenger OEA links dietary fat intake to satiety

GJ Schwartz, J Fu, G Astarita, X Li, S Gaetani… - Cell metabolism, 2008 - cell.com
The association between fat consumption and obesity underscores the need to identify
physiological signals that control fat intake. Previous studies have shown that feeding stimulates …

[HTML][HTML] Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine

J Fu, G Astarita, S Gaetani, J Kim, BF Cravatt… - Journal of Biological …, 2007 - ASBMB
… Antibody Generation—We constructed a glutathione S-transferase-linked peptide
comprising residues 38-53 of rat NAPE-PLD. The DNA fragment was amplified using primers …