… Skin wound healing is a complex process requiring sophisticated interactions between
inflammatory cells, peptide mediators, extracellular matrix molecules and the micro-…

… In summary, results presented in this article confirm that macrolides can suppress
neutrophil-dominated pulmonary inflammation and suggest that the effect is mediated through …

… The biphasic facilitatory-then-inhibitory response to azithromycin seen in healthy volunteers
is not so clearly detectable in COPD patients, only potential anti-inflammatory effects. …

… However, the molecular mechanism(s) of activity as well as the target cells for their action …
in lung tissue following azithromycin treatment is mediated through effects on alveolar …

… Amplification was performed using the following cycling conditions: 2 min at 50C, 10 min
at 95C, and 45 two-step cycles of 15 s at 95C and 60 s at 60C. Triplicate qRT-PCR analyses …

… diabetic (db/db) mouse is a commonly used model of impaired … that wound closure in db/db
mice is delayed owing to: (1) … this article is making through the number of times it’s been …

Azithromycin, a macrolide antibacterial, has been shown to modify the phenotype of
macrophages. We have investigated whether azithromycin in vitro is able to modulate the …

… is limited and the need for new and improved therapies remains. Due to complexity of the
disease, it is … fibrotic phase is predominant over inflammatory phase, which is important when …

… Weaker staining of white pulp compared to red pulp of spleen is in … Gentamicin labeled with
Texas Red fluorescent dye (GTTR) is the … To our knowledge this is the first report to describe …

Macrolide antibiotics inhibit the secretion of Th1 cytokines while their effects on the release
of Th2 cytokines are variable. We investigated molecular and cellular markers of Th1- and …