[HTML][HTML] Decreased mitochondrial pyruvate transport activity in the diabetic heart: role of mitochondrial pyruvate carrier 2 (MPC2) acetylation

SS Vadvalkar, S Matsuzaki, CA Eyster… - Journal of Biological …, 2017 - ASBMB
Alterations in mitochondrial function contribute to diabetic cardiomyopathy. We have
previously shown that heart mitochondrial proteins are hyperacetylated in OVE26 mice, a …

Metabolic inflexibility and protein lysine acetylation in heart mitochondria of a chronic model of type 1 diabetes

SS Vadvalkar, CN Baily, S Matsuzaki… - Biochemical …, 2013 - portlandpress.com
… Shraddha Vadvalkar performed the majority of the biochemical experiments, including
isolation of mitochondria, measurement of mitochondrial respiration and enzyme activities, and …

Cardiac insulin signaling regulates glycolysis through phosphofructokinase 2 content and activity

LB Bockus, S Matsuzaki, SS Vadvalkar… - Journal of the …, 2017 - Am Heart Assoc
Background The healthy heart has a dynamic capacity to respond and adapt to changes in
nutrient availability. Diabetes mellitus disrupts this metabolic flexibility and promotes …

[HTML][HTML] PPARα is essential for retinal lipid metabolism and neuronal survival

…, K Zhou, Y Takahashi, HG Matlock, SS Vadvalkar… - BMC biology, 2017 - Springer
Background Peroxisome proliferator activated receptor-alpha (PPARα) is a ubiquitously
expressed nuclear receptor. The role of endogenous PPARα in retinal neuronal homeostasis is …

A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer

…, J Henthorn, KM Humphries, SS Vadvalkar… - … of Pharmacology and …, 2015 - ASPET
Therapy for treatment-resistant breast cancer provides limited options and the response
rates are low. Therefore, the development of therapies with alternative chemotherapeutic …

Challenges and directions for semantic communication

V Rodoplu, SS Vadvalkar - International Conference on …, 2007 - ieeexplore.ieee.org
This paper aims to present ideas to bridge the gap between two conflicting views of information:
Shannon information, which is used to model physical layer information, and semantic …

Inhibition of mitochondrial respiration by phosphoenolpyruvate

CN Baily, RW Cason, SS Vadvalkar… - Archives of biochemistry …, 2011 - Elsevier
The cytosolic factors that influence mitochondrial oxidative phosphorylation rates are
relatively unknown. In this report, we examine the effects of phosphoenolpyruvate (PEP), a …

[BOOK][B] Characterization of mannitol accumulating T4 generation transgenic wheat exposed to drought stress

SS Vadvalkar - 2008 - search.proquest.com
Wheat is an important crop grown worldwide, and it is severely affected by the drought stress.
Sugars and sugar alcohols are known for protecting plants from drought stress. Among …

[PDF][PDF] ARTICLE INFO ABSTRACT Article history Received: 20/1/13 Available online

…, NB Ghiware, MH Ghante, MM Kumare, SM Vadvalkar - academia.edu
… Charge DM Water and remaining glycerine are transferred to stainless steel vessel in
which … Transfer it to stainless steel vessel and mix well. To the stainless steel vessel add the …

Improving decision making for drug candidates: A computational approach for benzthiazoles as antifungal

…, UD Deshpande, SS Pekamwar, SM Vadvalkar - 2007 - nopr.niscpr.res.in
To improve the decision making for selecting a molecule for synthesis from a set of virtually
designed antifungal compounds, four in silico approaches are discussed and their …