▪ Abstract Cardiac β-adrenergic receptors, which respond to neuronally released and circulating
catecholamines, are important regulators of cardiac function. Congestive heart failure, a …

Somatostatin is a tetradecapeptide that is widely distributed in the body. It acts on multiple
organs including brain, pituitary, gut, exocrine and endocrine pancreas, adrenals, thyroid, and …

Neocortical neuroblast cell lines were used to clone G-protein-coupled receptor (GPCR)
genes to study signaling mechanisms regulating cortical neurogenesis. One putative GPCR …

There is great therapeutic interest in manipulating (either enhancing or suppressing) G
protein-coupled receptor (GPCR) signal transduction. However, most current strategies are …

Hypothalamic obesity, a syndrome of intractable weight gain due to hypothalamic damage,
is an uncommon but devastating complication for children surviving brain tumors. We …

… of SR-A confers cell surface binding and uptake of gp96 and CRT, whereas genetic deletion
of SR-A … Data are also provided demonstrating that SR-A can direct bound ligands to an …

… As an example, a scavenger receptor belonging to class A will be designated as SR-A1,
where SR stands for scavenger receptor and is followed by a hyphen, then a capital letter …

Calreticulin and gp96 (GRP94) traffic associated peptides into the major histocompatibility
complex class-I cross-presentation pathway of antigen-presenting cells (APCs). Efficient …

… Statistical comparisons were made by repeated-measure ANOVA (force-frequency behavior
in isolated cells and muscle strips) and ANOVA followed by a Student-Newman-Keuls post …

We have investigated the stoichiometric relationship of proteins involved in beta-adrenergic-receptor-mediated
signal transduction in isolated rat cardiac myocytes. These cells contain …