… Lysosomal biogenesis requires the transcription factor TFEB, and Roczniak-Ferguson et al.
investigated the mechanisms by which lysosomal status controlled the activity of TFEB. They …

Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in
membrane remodelling, has a critical role in endocytic membrane fission events. The use of …

Dynamin 1 is a neuron-specific guanosine triphosphatase thought to be critically required for
the fission reaction of synaptic vesicle endocytosis. Unexpectedly, mice lacking dynamin 1 …

Addiction is a chronic relapsing disorder characterized by the loss of control over drug intake,
high motivation to obtain the drug, and a persistent craving for the drug. Accumulating …

Dorsal striatum is important for the development of drug addiction; however, a precise
understanding of the roles of striatopallidal (indirect) and striatonigral (direct) pathway neurons in …

… Petit, Agnes Roczniak-Ferguson, Shawn M. Ferguson; Recruitment of folliculin to lysosomes
supports the amino acid–dependent activation of Rag GTPases. J Cell Biol 30 September …

The MiT‐ TFE family of basic helix‐loop‐helix leucine‐zipper transcription factors includes
four members: TFEB , TFE 3, TFEC , and MITF . Originally described as oncogenes, these …

… We thank Frank Wilson and Agnes Roczniak-Ferguson for superb management and
maintenance of lab infrastructure; Wendolyn Hill for assistance with illustrations; and Louise Lucast …

Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted
pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative affect, …

… The conditional KO (floxed) and KO alleles of dynamin 1, 2 and 3 used in this study were
previously described (Ferguson et al., 2007; Ferguson et al., 2009; Raimondi et al., 2011). …