Enhancement of the hypotensive effects of intrathecally injected endocannabinoids by the entourage compound palmitoylethanolamide

…, E Adler-Graschinsky, SM Celuch - European journal of …, 2009 - Elsevier
The intrathecal (it) injection of 50 and 100 nmol anandamide to urethane anesthetized rats
induced a dose-dependent decrease in the mean blood pressure (−10.6±1.6 mmHg and −…

Stimulation of presynaptic β-adrenoceptors enhances [3H]-noradrenaline release during nerve stimulation in the perfused cat spleen

SM Celuch, ML Dubocovich… - British Journal of …, 1978 - ncbi.nlm.nih.gov
… 98 SM CELUCH, ML DUBOCOVICH & SZ LANGER … 100 SM CELUCH, ML
DUBOCOVICH & SZ LANGER … LANGER, SZ, ENERO, MA, ADLER-GRASCHINSKY, E …

Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats

…, E Adler-Graschinsky, SM Celuch - Naunyn-Schmiedeberg's …, 2003 - Springer
This study examined the effect of intrathecal (it) injection of the endocannabinoid anandamide
in urethane-anesthetized rats. The tip of the it cannula was positioned at the T 12 –L 1 …

Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats

ML Orliac, R Peroni, SM Celuch… - Journal of Pharmacology …, 2003 - ASPET
The aim of the present experiments was to study the effects of exogenously added anandamide
on transient norepinephrine (NE)-induced contractions in mesenteric beds isolated from …

Sex-linked differences in the vasorelaxant effects of anandamide in vascular mesenteric beds: role of oestrogens

…, E Adler-Graschinsky, SM Celuch - European journal of …, 2004 - Elsevier
Anandamide (0.01 to 10 μM) caused greater concentration-dependent reductions of the
contractile-induced responses to noradrenaline in female than in male mesenteric vascular …

Possible participation of spinal nitric oxide in the control of the blood pressure in anesthetized rats

M del Carmen Garcı́a, SM Celuch, E Adler-Graschinsky - Brain research, 1997 - Elsevier
In pentobarbital-anesthetized rats the intrathecal (it) injection of the nitric oxide (NO)
precursor, l-arginine (10 and 20 μmol), elicited a decrease in the mean blood pressure (MBP) …

Fructose-induced metabolic syndrome decreases protein expression and activity of intestinal P-glycoprotein

…, YC Godoy, SA Martinez, CI Ghanem, SM Celuch - Nutrition, 2015 - Elsevier
Objectves Metabolic syndrome (MetS) is a health disorder that increases the risk for
cardiovascular complications such as heart disease and type 2 diabetes. Some drugs used in …

Possible participation of histamine H3 receptors in the modulation of noradrenaline release from rat spinal cord slices

SM Celuch - European journal of pharmacology, 1995 - Elsevier
Rat spinal cord slices prelabelled with [ 3 H]noradrenaline were superfused with a medium
containing 1 μM desipramine plus 0.3 μM phentolamine. Histamine (0.01-10 μM) and the …

Hypotensive and hypertensive effects of catecholamines intrathecally injected in anesthetized rats

M del Carmen García, MA Enero, SM Celuch - Journal of the autonomic …, 1996 - Elsevier
The cardiovascular effects of catecholamines intrathecally (it) injected at the T 12 −L 1 level
were analyzed in pentobarbital anesthetized rats. Volumes of injection were not greater than …

Cardiotoxic Effects of the Antineoplastic Doxorubicin in a Model of Metabolic Syndrome: Oxidative Stress and Transporter Expression in the Heart

…, A Fellet, AM Balaszczuk, SM Celuch - Journal of …, 2021 - journals.lww.com
The aim of the present work was to examine whether metabolic syndrome–like conditions in
rats with fructose (F) overload modify the cardiotoxic effects induced by doxorubicin (DOX) …