User profiles for S V Shah

Spandan Shah

Beth Israel Deaconess, Harvard Medical School
Verified email at bidmc.harvard.edu
Cited by 1816

[PDF][PDF] The role of iron in diabetes and its complications

S Swaminathan, VA Fonseca, MG Alam, SV Shah - Diabetes care, 2007 - Citeseer
The central importance of iron in the pathophysiology of disease is derived from the ease
with which iron is reversibly oxidized and reduced. This property, while essential for its …

Oxidant mechanisms in toxic acute renal failure

…, N UEDA, PD WALKER, SV SHAH - Drug metabolism …, 1999 - Taylor & Francis
Over the last decade, there is accumulating evidence for a role of reactive oxygen metabolites
in the pathogenesis of a variety of renal diseases, including gentamicin, glycerol, cisplatin, …

Oxidant mechanisms in toxic acute renal failure

R Baliga, N Ueda, PD Walker, SV Shah - American Journal of Kidney …, 1997 - Elsevier
… Abul-Ezz SR, Walker PD, Shah SV: Role of glutathione in an animal model of myoglobinuric
acute … Walker PD, Das C, Shah SV: Cyclosporin A induced lipid peroxidation in renal cortical …

[HTML][HTML] Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury

RL Mehta, JA Kellum, SV Shah, BA Molitoris, C Ronco… - Critical care, 2007 - Springer
Introduction Acute kidney injury (AKI) is a complex disorder for which currently there is no
accepted definition. Having a uniform standard for diagnosing and classifying AKI would …

Induction of myeloid‐derived suppressor cells by tumor exosomes

…, Z Deng, J Wang, Z Cheng, SV Shah… - … journal of cancer, 2009 - Wiley Online Library
Myeloid‐derived suppressor cells (MDSCs) promote tumor progression. The mechanisms of
MDSC development during tumor growth remain unknown. Tumor exosomes (T‐exosomes) …

Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance

…, J Wang, X Xiang, S Zhang, X Zhuang, SV Shah… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE We sought to determine whether exosome-like vesicles (ELVs) released from
adipose tissue play a role in activation of macrophages and subsequent development of …

Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats.

PD Walker, SV Shah - The Journal of clinical investigation, 1988 - Am Soc Clin Investig
The protective effect of hydroxyl radical scavengers and iron chelators has strongly implicated
the hydroxyl radical in several models of tissue injury. Based on in vitro studies showing …

Cost-effectiveness of dabigatran for stroke prophylaxis in atrial fibrillation

SV Shah, BF Gage - Circulation, 2011 - Am Heart Assoc
… We thank Kathryn Lindley, MD, for her help with interpreting data from published
literature and Jay Shah, MD, for his comments on an earlier version of the manuscript. …

In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity

R Baliga, Z Zhang, M Baliga, N Ueda, SV Shah - Kidney international, 1998 - Elsevier
SHAH SV, WALKER PD: Evidence suggesting a role for hydroxyl radical in glycerol-induced …
ABUL-EZZ SR, WALKER PD, SHAH SV: Role of glutathione in an animal model of …

[HTML][HTML] Autophagy in acute kidney injury

GP Kaushal, SV Shah - Kidney international, 2016 - Elsevier
Autophagy is a conserved multistep pathway that degrades and recycles damaged organelles
and macromolecules to maintain intracellular homeostasis. The autophagy pathway is …